Rab L5, also known as Rab45, is a member of the Rab family of small GTPases, which are essential regulators of vesicular trafficking in eukaryotic cells. Unlike many other Rab GTPases, Rab L5 has an atypically large N-terminal extension. This region allows Rab L5 to participate in unique interactions, thereby having distinct cellular roles. Rab L5 is known to play a significant role in cellular processes such as endocytosis and the regulation of endosomal trafficking. It is also involved in cell signaling pathways, helping in the modulation of cellular responses to external stimuli.
Rab L5 has been implicated in various physiological processes, including immune responses and cellular homeostasis. The expression and activity of Rab L5 are thought to be tightly regulated, as aberrant Rab L5 signaling could lead to pathological conditions. Further research is essential to fully understand the biological significance and the regulatory mechanisms of Rab L5, which could provide insights into the development of strategies for diseases associated with vesicular trafficking and cellular signaling abnormalities.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone, a synthetic glucocorticoid, may enhance Rab L5 expression by modulating cellular immune responses and inflammation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid may influence Rab L5 expression during cellular differentiation and development processes. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA, a PKC activator, might upregulate Rab L5 expression by activating protein kinase C (PKC) pathways. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor that may promote Rab L5 expression by inducing hyperacetylation of histones. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
May induce Rab L5 by increasing intracellular cAMP levels and activating PKA. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A demethylating agent that might promote Rab L5 expression by DNA demethylation. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that might stabilize Rab L5 by blocking its degradation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that may indirectly influence Rab L5 expression by modulating PI3K/Akt signaling pathways. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
A compound that might enhance Rab L5 expression through HDAC inhibition and increased histone acetylation. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
A calcium ionophore that might affect Rab L5 expression by altering intracellular calcium concentrations. |