PYGM Inhibitors
Items 1 to 10 of 14 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride | 100991-92-2 | sc-220553 sc-220553A | 10 mg 25 mg | $431.00 $1025.00 | 2 | |
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride acts as a potent inhibitor of glycogen phosphorylase, exhibiting unique molecular interactions that disrupt substrate binding. Its structural features facilitate specific electrostatic interactions, influencing the enzyme's active site conformation. The compound's kinetic profile reveals a competitive inhibition mechanism, effectively altering the reaction rate. Furthermore, its solubility characteristics enable versatile applications in biochemical assays, enhancing the study of glycogen metabolism pathways. | ||||||
Dichloroacetic acid | 79-43-6 | sc-214877 sc-214877A | 25 g 100 g | $61.00 $128.00 | 5 | |
Inhibits pyruvate dehydrogenase kinase, indirectly influencing the metabolic pathways related to PYGM, potentially modulating its activity through altered energy metabolism. | ||||||
CP-91149 | 186392-40-5 | sc-396026A sc-396026 sc-396026B sc-396026C sc-396026D | 5 mg 10 mg 25 mg 50 mg 100 mg | $163.00 $204.00 $398.00 $500.00 $714.00 | 1 | |
CP-91149 functions as a selective inhibitor of glycogen phosphorylase, characterized by its ability to form stable complexes with the enzyme. This compound exhibits unique steric hindrance that alters the enzyme's conformation, impacting substrate accessibility. Its reaction kinetics suggest a non-competitive inhibition model, which modifies the catalytic efficiency without affecting substrate affinity. Additionally, CP-91149's hydrophilic nature enhances its interaction with aqueous environments, facilitating detailed mechanistic studies. | ||||||
Sodium azide | 26628-22-8 | sc-208393 sc-208393B sc-208393C sc-208393D sc-208393A | 25 g 250 g 1 kg 2.5 kg 100 g | $43.00 $155.00 $393.00 $862.00 $90.00 | 8 | |
Inhibits cellular respiration by interfering with cytochrome c oxidase, impacting the energy production pathways and potentially affecting PYGM activity indirectly through altered cellular energetics. | ||||||
Sodium Fluoride | 7681-49-4 | sc-24988A sc-24988 sc-24988B | 5 g 100 g 500 g | $40.00 $46.00 $100.00 | 26 | |
Inhibits various phosphatases, potentially influencing the cellular signaling pathways related to PYGM regulation. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
Acts as a competitive inhibitor of glucose metabolism, indirectly affecting the energy balance and potentially influencing PYGM through altered cellular metabolism. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Inhibits adenosine receptors and cAMP phosphodiesterase, influencing cellular signaling cascades that might indirectly modulate PYGM activity. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
Inhibits glycogen synthase kinase-3 (GSK-3), potentially impacting glycogen metabolism pathways and influencing PYGM indirectly. | ||||||
3-Bromo-7-nitroindazole | 74209-34-0 | sc-200347 sc-200347A | 5 mg 25 mg | $20.00 $26.00 | 1 | |
Inhibits nitric oxide synthase (NOS), potentially affecting cellular signaling pathways related to PYGM regulation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Inhibits phosphoinositide 3-kinase (PI3K), potentially affecting the AKT/mTOR pathway and influencing cellular processes related to PYGM indirectly. | ||||||