Purβ Activators
Purβ activators are a class of compounds that influence the functional activity of Purβ, a protein that is involved in various cellular processes and signaling pathways. For instance, compounds like A23187 and Ionomycin, which increase intracellular calcium levels, can enhance the activity of Purβ which is involved in calcium-dependent signaling pathways. Similarly, compounds like Epinephrine, which activates adrenergic receptors, can enhance the function of Purβ, which is implicated in signaling pathways downstream of these receptors.
Furthermore, inhibitors of kinases and phosphatases, such Okadaic Acid, can affect the phosphorylation status of proteins within signaling pathways that involve Purβ, thereby influencing its function. Lastly, compounds like Dexamethasone that affect a wide array of signaling pathways via the glucocorticoid receptor can also indirectly enhance the activity of Purβ.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 is a calcium ionophore that promotes the rapid influx of calcium ions into cells. As Purβ is known to be involved in calcium-dependent signal transduction, this influx can indirectly enhance its functional activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a potent activator of Protein Kinase C (PKC), a kinase involved in signal transduction pathways that Purβ may participate in. By activating PKC, PMA could indirectly enhance the functional activity of Purβ. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
Epinephrine is a hormone and neurotransmitter that activates adrenergic receptors, leading to activation of several signal transduction pathways, potentially including those involving Purβ. | ||||||
Deferoxamine mesylate | 138-14-7 | sc-203331 sc-203331A sc-203331B sc-203331C sc-203331D | 1 g 5 g 10 g 50 g 100 g | $255.00 $1039.00 $2866.00 $4306.00 $8170.00 | 19 | |
Deferoxamine is an iron chelator that can indirectly affect the function of Purβ through its role in iron-dependent signaling pathways. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $45.00 $56.00 $183.00 | 142 | |
Sodium Orthovanadate is a potent inhibitor of phosphatases which could indirectly affect the phosphorylation status of proteins within pathways that Purβ is part of. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin is a calcium ionophore, like A23187, and could similarly affect the functional activity of Purβ by increasing intracellular calcium levels. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
Okadaic Acid is a potent inhibitor of protein phosphatases PP1 and PP2A, which could indirectly affect the functional activity of Purβ by altering the balance of protein phosphorylation in cells. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide is a topoisomerase II inhibitor. By affecting DNA topology and therefore transcription, this compound could indirectly influence Purβ, which is known to interact with DNA and RNA. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a glucocorticoid that affects numerous signaling pathways via the glucocorticoid receptor. Through these pathways, it could indirectly affect the functional activity of Purβ. | ||||||