pS2 Activators
The chemicals listed above are known to indirectly influence the expression or function of TFF1 (pS2) through various mechanisms. TFF1, as part of the trefoil factor family, plays a key role in mucosal protection and repair, particularly in the gastrointestinal tract. Its expression is often regulated by hormonal and environmental factors. Estradiol, a natural form of estrogen, is known to upregulate TFF1 expression, especially in breast tissue. Selective estrogen receptor modulators like Tamoxifen and Raloxifene can also influence TFF1 expression due to their estrogenic activity.
Epigenetic modulators such as Trichostatin A and 5-Aza-2'-deoxycytidine can alter gene expression patterns, potentially impacting TFF1 levels. Retinoic Acid, a derivative of Vitamin A, is involved in gene expression modulation and could influence TFF1. Growth factors and their inhibitors, such as EGF and Gefitinib, can modulate signaling pathways that may have downstream effects on TFF1 expression. Natural compounds like Sulforaphane, Curcumin, and Resveratrol, known for their various biological activities, could potentially modulate TFF1 expression.Lastly, Vitamin D3, which has a role in regulating gene expression, might also influence TFF1 levels.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
A form of estrogen; TFF1 expression is known to be upregulated by estrogen, particularly in breast tissue. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
A selective estrogen receptor modulator; can indirectly influence TFF1 expression through estrogenic activity. | ||||||
Raloxifene | 84449-90-1 | sc-476458 | 1 g | $802.00 | 3 | |
Another selective estrogen receptor modulator, known to affect estrogen-responsive genes like TFF1. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, which can modulate gene expression, potentially affecting TFF1 levels. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor, potentially influencing TFF1 expression by altering DNA methylation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Involved in gene expression modulation; may influence TFF1 expression. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $63.00 $114.00 $218.00 $349.00 | 74 | |
An EGFR inhibitor, could indirectly affect TFF1 expression by modulating EGFR signaling. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
A compound in cruciferous vegetables known for its effects on cellular pathways, potentially influencing TFF1. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenol with various biological effects, potentially modulating TFF1 expression. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Involved in the regulation of gene expression, may have an indirect effect on TFF1 levels. | ||||||