PRPF38B Activators form a distinct category of chemical compounds that have attracted attention within the field of molecular biology and cellular research. These activators are designed to modulate the activity of the PRPF38B gene, with PRPF38B denoting Pre-mRNA Processing Factor 38B. This gene is a protein-coding element present in the human genome and is associated with critical cellular processes related to pre-mRNA splicing. Pre-mRNA splicing is an essential step in gene expression where non-coding introns are removed, and exons are ligated together to form mature mRNA transcripts. PRPF38B Activators constitute a group of molecules engineered to enhance or stimulate the expression and function of the PRPF38B gene, ultimately leading to an increase in the activity of the associated protein.
The mechanism through which PRPF38B Activators exert their effects typically involves their interaction with specific regulatory elements within the PRPF38B gene, such as promoter regions or enhancer sequences. These interactions facilitate the upregulation of gene transcription, resulting in heightened synthesis of the PRPF38B protein. The PRPF38B protein is integral to the spliceosome, a multi-protein complex responsible for precise and accurate pre-mRNA splicing. As scientists delve deeper into the functions and potential implications of PRPF38B activation, the development and refinement of PRPF38B Activators hold promise for advancing our understanding of pre-mRNA processing, gene regulation, and the broader role of PRPF38B in cellular functionality and molecular pathways, potentially revealing novel aspects of gene expression and mRNA maturation.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $63.00 $174.00 | ||
Butyric acid can inhibit histone deacetylases, leading to a more relaxed chromatin state and potentially an increase in gene expression, including PRPF38B. | ||||||
Dichloroacetic acid | 79-43-6 | sc-214877 sc-214877A | 25 g 100 g | $60.00 $125.00 | 5 | |
Dichloroacetic acid can alter cellular metabolism, which might indirectly trigger changes in gene expression, possibly affecting PRPF38B. | ||||||
Mifepristone | 84371-65-3 | sc-203134 | 100 mg | $60.00 | 17 | |
As a glucocorticoid receptor antagonist, mifepristone can affect transcriptional regulation, potentially altering PRPF38B expression. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram is a phosphodiesterase inhibitor, leading to increased cAMP levels, which may affect the transcription of various genes, including PRPF38B. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
SAHA is a histone deacetylase inhibitor that can cause chromatin remodeling and potentially increase expression of certain genes, including PRPF38B. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
Geldanamycin binds to heat shock protein 90 (Hsp90) and may affect the stability and function of client proteins, potentially influencing PRPF38B expression. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 is a proteasome inhibitor that can affect protein turnover and may lead to altered gene expression, potentially impacting PRPF38B. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
DMSO can affect cell differentiation and gene expression, which may have an indirect effect on the expression of PRPF38B. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Azacitidine is a nucleoside analog that inhibits DNA methyltransferase, which may lead to changes in gene expression, including PRPF38B. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Disulfiram can modulate proteasome activity and affect transcription factor function, potentially altering gene expression such as PRPF38B. | ||||||