Dimethyl Sulfoxide (DMSO) CAS: 67-68-5
MF: C2H6OS
MW: 78.13

Dimethyl Sulfoxide (DMSO) (CAS 67-68-5)

Dimethyl Sulfoxide (DMSO) | CAS 67-68-5 is rated 4.4 out of 5 by 7.
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Alternate Names: Dimethyl Sulfoxide is also known as DMSO.
Application: Dimethyl Sulfoxide (DMSO) is a versatile, highly polar, aprotic organic solvent used in chemical and polymerase chain reactions, and as a cryoprotectant
CAS Number: 67-68-5
Purity: ≥99%
Molecular Weight: 78.13
Molecular Formula: C2H6OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Dimethyl Sulfoxide (DMSO) is a solvent with wide ranging applications in biological research. Dimethyl Sulfoxide (DMSO) can be used as solvent for acetylene, sulfur dioxide and other gases, as an anti-freeze or hydraulic fluid when mixed with water, as a paint or varnish remover and as a solvent for Orlon and other synthetic fibres. Dimethyl Sulfoxide (DMSO) is also used for polymerization and cyanide reactions and in industrial cleaners, pesticides, medicine (anti-inflammatory), veterinary medicine and pharmaceuticals. Dimethyl Sulfoxide (DMSO) (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination. As a PCR cosolvent, Dimethyl Sulfoxide (DMSO) may help improve yields, especially in long PCR. Dimethyl Sulfoxide is also known as DMSO, Methyl sulfoxide, Dimethyl sulphoxide, and Methylsulfinylmethane.


References

1. Sweat, F.W. and Epstein, W.W. 1967. J. Org. Chem. 32(3): 835-838. PMID: 6042131

2. Chakrabarti, R. and Schutt, C.E. 2001. Gene. 274(1-2): 293-298. PMID: 11675022

3. Pegg, D.E. 2007. Methods Mol. Biol. 368 : 39-57. PMID: 18080461

Usage :
To prepare a sterile filtered DMSO solution, it is recommended to use a teflon or nylon membrane. Cellulose acetate membranes are not recommended
Appearance :
Clear, colorless liquid
Physical State :
Liquid
Solubility :
Soluble in water, ethanol, ether, benzene, chloroform, and acetone.
Storage :
Store at room temperature
Melting Point :
16-19° C
Boiling Point :
189° C
Density :
1.10 g/mL
Refractive Index :
n20D 1.48 (lit.)
IC50 :
HII4E cells : IC50 = 199 µg/ml (mouse)
Ki Data :
Choline acetylase: Ki= 25000000 nM (Rattus norvegicus)
pK Values :
pKa: -4.54
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
RTECS :
PV6210000
PubChem CID :
679
Merck Index :
14: 3259
MDL Number :
MFCD00002089
EC Number :
200-664-3
Beilstein Registry :
506008
SMILES :
CS(=O)C

Download SDS (MSDS)

Certificate of Analysis

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Dimethyl Sulfoxide (DMSO) (CAS 67-68-5)  Product Citations

See how others have used Dimethyl Sulfoxide (DMSO) (CAS 67-68-5). Click on the entry to view the PubMed entry .

Citations 1 to 10 of 67 total

PMID: # 31357009  Park, SY.|Yoo, YM.|Jung, EM.|Jeung, EB.| et al. 2019. Brain Res. Bull. 152: 225-235.

PMID: # 31167152  Tian, Z.|Luo, Y.|Zhu, J.|Hua, X.|Xu, J.|Huang, C.|Jin, H.|Huang, H.|Huang, C.| et al. 2019. Biochim Biophys Acta Gene Regul Mech. 1862: 822-833.

PMID: # 31393749  Yamada, S.|Lav, R.|Li, J.|Tucker, AS.|Green, JBA.| et al. 2019. J. Dent. Res. 22034519869307.

PMID: # 31385138  Foroughi, K.|Khaksari, M.|Rahmati, M.|Bitaraf, FS.|Shayannia, A.| et al. 2019. Neurochem. Res.

PMID: # 30864712  Xiao, L.|Luo, Y.|Tai, R.|Zhang, N.| et al. 2019. Mol Med Rep. 19: 3555-3563.

PMID: # 30595207  Nusair, SD.|Almasaleekh, MJ.|Abder-Rahman, H.|Alkhatatbeh, M.| et al. 2019. Mutat Res Genet Toxicol Environ Mutagen. 837: 34-41.

PMID: # 29301067  Kyriakakis, P.|Catanho, M.|Hoffner, N.|Thavarajah, W.|Hu, VJ.|Chao, SS.|Hsu, A.|Pham, V.|Naghavian, L.|Dozier, LE.|Patrick, GN.|Coleman, TP.| et al. 2018. ACS Synth Biol. 7: 706-717.

PMID: # 30296733  Khalil, AM.|Abu Samrah, HM.| et al. 2018. Res. Vet. Sci. 120: 94-100.

PMID: # 30261499  Meng, F.|Zhao, Y.|Wang, B.|Li, B.|Sheng, Y.|Liu, M.|Li, H.|Xiu, R.| et al. 2018. Cell. Physiol. Biochem. 49: 2371-2381.

PMID: # 30545309  Liu, CH.|Hua, N.|Fu, X.|Pan, YL.|Li, B.|Li, XD.| et al. 2018. BMC Cardiovasc Disord. 18: 236.

Citations 1 to 10 of 67 total

Dear Sir/ Madam, A customer of ours needs 50 x 5ml/vial of DMSO. Please kindly quote if you could provide us with such a pack

Asked by: Hsing
Thank you for your question. Please call our Asian Support office toll-free at 800-820-8626, email [email protected], or contact us by live chat.
Answered by: Technical Support
Date published: 2018-01-31

Is this chemical usable for food?

Asked by: sg1020v
Thank you for your question. No, our chemicals are intended for research use only. They are not recommended for diagnostic or therapeutic use, and they are definitely not intended for use in consumable goods such as food.
Answered by: Technical Support
Date published: 2020-03-10

Can you offer it in medical grade?

Asked by: chemsd02
Thank you for your question. sc-202581 (Dimethyl Sulfoxide (DMSO), CAS 67-68-5) cannot be offered in medical grade.
Answered by: Chemical Support 10
Date published: 2017-04-06

Is the ChemCruz Dimethyl Sulfoxide (DMSO) sc-202581 sterile? 

Asked by: SCM4
This chemical, DMSO, is not considered sterile.
Answered by: Chemical Support 1
Date published: 2017-03-09

Is this product ACS grade?

Asked by: hawkeye11
This chemical, Dimethyl Sulfoxide (CAS 67-68-5), is ACS grade.
Answered by: Chemical Support 1
Date published: 2017-03-09

solicito su direccion en Santa Cruz Bolivia

Asked by: Anonymous
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Rated 1 out of 5 by from Made my media cloudy For some reason, it makes my freezing medium cloudy - either due to some microbial contamination or purity. I added Fisher DMSO side-by-side and had no issues. The price is good, though.
Date published: 2020-09-18
Rated 5 out of 5 by from great We use this product effect is very good, the solvent is very easy to use, can provide high quality results!
Date published: 2017-02-07
Rated 5 out of 5 by from Good! This highly polar organic solvent being used in many chemical and biological research can uniquely provide solubility to certain very polar small molecules with a high quality.
Date published: 2017-01-22
Rated 5 out of 5 by from good The solvent is very easy to use! I used it and had good experimental results! My partner and I are satisfied with it!
Date published: 2016-11-19
Rated 5 out of 5 by from Works fine We used to use this product and very much satisfied with the quality.
Date published: 2016-11-01
Rated 5 out of 5 by from We use it in the lab and it works fine We use it in the lab and it works fine.
Date published: 2015-09-22
Rated 5 out of 5 by from Use this routinely in our lab and has good quality Use this routinely in our lab and has good quality.
Date published: 2015-09-02
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