Dimethyl Sulfoxide (DMSO) CAS: 67-68-5
MW: 78.13

Dimethyl Sulfoxide (DMSO) (CAS 67-68-5)

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Dimethyl Sulfoxide (DMSO) is rated 5.0 out of 5 by 6.
Alternate Names: Dimethyl Sulfoxide is also known as DMSO.
Application: Dimethyl Sulfoxide (DMSO) is a versatile, highly polar, aprotic organic solvent used in chemical and polymerase chain reactions, and as a cryoprotectant vitrification agent.
CAS Number: 67-68-5
Purity: ≥99%
Molecular Weight: 78.13
Molecular Formula: C2H6OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Dimethyl Sulfoxide (DMSO) is a solvent with wide ranging applications in biological research. Dimethyl Sulfoxide (DMSO) can be used as solvent for acetylene, sulfur dioxide and other gases, as an anti-freeze or hydraulic fluid when mixed with water, as a paint or varnish remover and as a solvent for Orlon and other synthetic fibres. Dimethyl Sulfoxide (DMSO) is also used for polymerization and cyanide reactions and in industrial cleaners, pesticides, medicine (anti-inflammatory), veterinary medicine and pharmaceuticals. Dimethyl Sulfoxide (DMSO) (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination. As a PCR cosolvent, Dimethyl Sulfoxide (DMSO) may help improve yields, especially in long PCR. Dimethyl Sulfoxide is also known as DMSO, Methyl sulfoxide, Dimethyl sulphoxide, and Methylsulfinylmethane.


1. Sweat, F.W. and Epstein, W.W. 1967. J. Org. Chem. 32(3): 835-838. PMID: 6042131

2. Chakrabarti, R. and Schutt, C.E. 2001. Gene. 274(1-2): 293-298. PMID: 11675022

3. Pegg, D.E. 2007. Methods Mol. Biol. 368 : 39-57. PMID: 18080461

Usage :
To prepare a sterile filtered DMSO solution, it is recommended to use a teflon or nylon membrane. Cellulose acetate membranes are not recommended
Appearance :
Clear, colorless liquid
Physical State :
Solubility :
Soluble in water, ethanol, ether, benzene, chloroform, and acetone.
Storage :
Store at room temperature
Melting Point :
16-19° C
Boiling Point :
189° C
Density :
1.10 g/mL
Refractive Index :
n20D 1.48 (lit.)
IC50 :
HII4E cells : IC50 = 199 µg/ml (mouse)
Ki Data :
Choline acetylase: Ki= 25000000 nM (Rattus norvegicus)
pK Values :
pKa: -4.54
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 3259
MDL Number :
EC Number :
Beilstein Registry :

Download SDS (MSDS)

Certificate of Analysis

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Dimethyl Sulfoxide (DMSO) (CAS 67-68-5)  Product Citations

See how others have used Dimethyl Sulfoxide (DMSO) (CAS 67-68-5). Click on the entry to view the PubMed entry .

Citations 1 to 10 of 112 total

PMID: # 35257373  Guzmán-Salas, S.|Weber, A.|Malci, A.|Lin, X.|Herrera-Molina, R.|Cerpa, W.|Dorador, C.|Signorelli, J.|Zamorano, P.| et al. 2022. J Neurochem. 161: 335-349.

PMID: # 35814898  Bicaklioglu, G.|Pirhan, D.|Yazir, Y.|Duruksu, G.|Furat Rencber, S.|Yuksel, N.| et al. 2022. Int J Ophthalmol. 15: 914-923.

PMID: # 35057038  Tarar, A.|Alyami, EM.|Peng, CA.| et al. 2022. Pharmaceutics. 14:

PMID: # 35097308  Vörös-Horváth, B.|Živković, P.|Bánfai, K.|Bóvári-Biri, J.|Pongrácz, J.|Bálint, G.|Pál, S.|Széchenyi, A.| et al. 2022. ACS Omega. 7: 3240-3253.

PMID: # 35225464  Salmani Javan, E.|Lotfi, F.|Jafari-Gharabaghlou, D.|Mousazadeh, H.|Dadashpour, M.|Zarghami, N.| et al. 2022. Asian Pac J Cancer Prev. 23: 519-527.

PMID: # 35192546  Valet, C.|Magnen, M.|Qiu, L.|Cleary, SJ.|Wang, KM.|Ranucci, S.|Grockowiak, E.|Boudra, R.|Conrad, C.|Seo, Y.|Calabrese, DR.|Greenland, JR.|Leavitt, AD.|Passegué, E.|Mendez-Ferrer, S.|Swirski, FK.|Looney, MR.| et al. 2022. J Clin Invest.

PMID: # 35714682  Liu, J.|Lin, Y.|Yang, Y.|Guo, Y.|Shang, Y.|Zhou, B.|Liu, T.|Fan, J.|Wei, C.| et al. 2022. Biochem Pharmacol. 202: 115149.

PMID: # 35079373  Naderi, R.|Gholizadeh-Ghaleh Aziz, S.|Haghigi-Asl, AS.| et al. 2022. Ann Med Surg (Lond). 73: 103240.

PMID: # 35273602  Yang, Q.|Burkardt, AC.|Sunkara, LT.|Xiao, K.|Zhang, G.| et al. 2022. Front Immunol. 13: 819222.

PMID: # 34258288  Haddad, M.| et al. 2021. Biomed Res Int. 2021: 9979768.

Citations 1 to 10 of 112 total

Dear Sir/ Madam, A customer of ours needs 50 x 5ml/vial of DMSO. Please kindly quote if you could provide us with such a pack

Asked by: Hsing
Thank you for your question. Please call our Asian Support office toll-free at 800-820-8626, email [email protected], or contact us by live chat.
Answered by: Technical Support
Date published: 2018-01-31

Is this chemical usable for food?

Asked by: sg1020v
Thank you for your question. No, our chemicals are intended for research use only. They are not recommended for diagnostic or therapeutic use, and they are definitely not intended for use in consumable goods such as food.
Answered by: Technical Support
Date published: 2020-03-10

Can you offer it in medical grade?

Asked by: chemsd02
Thank you for your question. sc-202581 (Dimethyl Sulfoxide (DMSO), CAS 67-68-5) cannot be offered in medical grade.
Answered by: Chemical Support 10
Date published: 2017-04-06

Is the ChemCruz Dimethyl Sulfoxide (DMSO) sc-202581 sterile? 

Asked by: SCM4
This chemical, DMSO, is not considered sterile.
Answered by: Chemical Support 1
Date published: 2021-03-21

Is this product ACS grade?

Asked by: hawkeye11
This chemical, Dimethyl Sulfoxide (CAS 67-68-5), is ACS grade.
Answered by: Chemical Support 1
Date published: 2017-03-09
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