The chemical class of PLU-1 Activators encompasses a range of compounds that indirectly influence the activity of PLU-1, primarily through their roles in modulating epigenetic regulation and gene expression. These activators do not directly interact with PLU-1 but create an environment conducive to its functional role in chromatin remodeling and transcriptional regulation. Compounds such as 5-Azacytidine, Trichostatin A, and Sodium butyrate function by modifying the epigenetic landscape. By altering DNA methylation and histone acetylation, these compounds can affect gene expression patterns, potentially enhancing the role of PLU-1 in transcriptional regulation. The changes in chromatin structure and gene expression directly impact the cellular functions in which PLU-1 is involved, particularly in the removal of methyl groups from histone H3.
Other compounds in this class, including Curcumin, Resveratrol, and Retinoic Acid, operate through diverse mechanisms but can influence PLU-1's activity in gene expression regulation and chromatin dynamics. For example, Curcumin and Resveratrol, with their broad biological activities, might modulate signaling pathways leading to the activation or enhanced functionality of PLU-1 in various cellular contexts, such as cell differentiation and development.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, which could indirectly affect PLU-1 by altering global DNA methylation and gene expression patterns. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, potentially influencing PLU-1 activity in chromatin remodeling and transcription regulation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Another histone deacetylase inhibitor, may affect chromatin structure and indirectly modulate PLU-1 activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Influences various signaling pathways; could modulate PLU-1's role in gene expression and chromatin dynamics. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Affects signaling pathways and gene expression, potentially modulating PLU-1 activity in epigenetic regulation. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Regulates gene expression, potentially affecting PLU-1's function in chromatin modification and transcriptional control. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A metabolite of Vitamin A, involved in gene regulation, could influence PLU-1 activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A phytoestrogen affecting various signaling pathways, potentially influencing PLU-1's epigenetic regulation functions. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
Influences metabolic pathways, potentially affecting PLU-1's role in chromatin remodeling and gene expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A glucocorticoid affecting gene expression, potentially influencing PLU-1 in epigenetic control. | ||||||