Date published: 2026-4-4

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PKA Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PKA Antibodies for various research applications. PKA Antibodies are compatible with western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Protein Kinase A (PKA) plays a crucial role in cellular signaling pathways, regulating processes such as metabolism, gene expression, and cell growth. By phosphorylating specific serine and threonine residues on target proteins, PKA influences numerous physiological responses, making it a key player in maintaining cellular homeostasis. Understanding the function and regulation of PKA is essential for elucidating its involvement in various diseases, including cancer and cardiovascular disorders. PKA monoclonal antibodies enable precise detection and quantification of PKA expression levels across different cell types and tissues. Researchers can effectively track PKA activity and localization in cellular compartments using multiple experimental approaches. The high specificity of PKA monoclonal antibodies from Santa Cruz Biotechnology supports researchers worldwide in advancing our understanding of cellular signaling mechanisms and disease pathways.

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PKA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PKA Iα reg Antibody (20)

sc-136231mouse IgG1FL (h)WB, IPm, r, h and canine
11
(4)

PKA Iα/β reg Antibody (B-6)

sc-271125mouse IgG2b κ246-335 (h)WB, IP, IF, IHC(P), ELISAm, r, h
5
(8)

PKA Iα/β reg Antibody (G-6)

sc-271446mouse IgG1 κ246-335 (h)WB, IP, IF, ELISAm, r, h
1
(1)

PKA Iβ reg Antibody (QR-7)

sc-100414mouse IgG2a κ1-91 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(3)

PKA IIα reg Antibody (H-12)

sc-137220mouse IgG2a κ21-100 (deletion 39-54) (h)WB, IP, IF, IHC(P), ELISAh
4
(4)

PKA IIα reg Antibody (Hs-36)

sc-51630mouse IgM(h)WB, IFh

new

(1)

PKA IIβ reg Antibody (C-2)

sc-376778mouse IgG3 κ21-110 (h)WB, IP, IF, ELISAm, r, h
14
(5)

PKA Phosphopeptide Substrate Antibody (BDI251)

sc-56941mouse IgG1N/AELISANSR
1
(1)

PKAα cat Antibody (A-2)

sc-28315mouse IgG2a κ322-351 (h)WB, IP, IF, IHC(P), ELISAm, r, h
45
(16)

PKAα cat Antibody (C-7)

sc-48412mouse IgG2a κ322-351 (h)WB, IP, IF, IHC(P), ELISAm, r, h
5
(8)

PKAα cat Antibody (B-5)

sc-28316mouse IgG1 κ322-351 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(5)

PKAα cat Antibody (F-4)

sc-515038mouse IgG1 κ31-48 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(0)

PKAα cat Antibody (H-8)

sc-515039mouse IgG2a κ31-48 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(0)

PKAα/β cat Antibody (3C1)

sc-52153mouse IgG1(bovine)WB, IP, ELISAh and bovine

new

(1)

PKAα/β cat Antibody (62A C2A)

sc-81174mouse IgG1(bovine)WB, IFbovine

new

(1)

PKAα/β/γ cat Antibody (B-4)

sc-365615mouse IgG2b κ226-320 (h)WB, IP, IF, ELISAm, r, h
22
(6)

PKAα/β/γ cat Antibody (G-6)

sc-390548mouse IgG1 κ231-286 (h)WB, IP, IF, ELISAm, r, h
13
(4)

PKAγ cat Antibody (A-4)

sc-514087mouse IgG1 κ322-350 (h)WB, IP, IF, IHC(P), ELISAm, r, h, mink
1
(1)

Phospho-Specific PKA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-PKA IIα reg Antibody (C-5)

sc-377575mouse IgM κSer 96 (m)WB, IP, IF, ELISAm, r, h
6
(3)

p-PKA IIβ reg Antibody (pS114.20A)

sc-293036mouse IgG1 κSer 114 (h)WB, IP, IFm, r, h
3
(5)

PKA CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PKA Iα reg CRISPR/Cas9 KO Plasmid (h)

sc-402036hGene KnockoutGFP0
(0)

PKA Iα reg HDR Plasmid (h)

sc-402036-HDRhHomology Directed RepairPuromycin0
(0)

PKA Iα reg CRISPR/Cas9 KO Plasmid (m)

sc-422400mGene KnockoutGFP0
(0)

PKA Iβ reg CRISPR/Cas9 KO Plasmid (h)

sc-418321hGene KnockoutGFP0
(0)

PKA Iβ reg HDR Plasmid (h)

sc-418321-HDRhHomology Directed RepairPuromycin0
(0)

PKA IIα reg CRISPR/Cas9 KO Plasmid (h)

sc-401080hGene KnockoutGFP0
(0)

PKA IIα reg HDR Plasmid (h)

sc-401080-HDRhHomology Directed RepairPuromycin0
(0)

PKAα cat CRISPR/Cas9 KO Plasmid (h2)

sc-400262-KO-2hGene KnockoutGFP0
(0)

PKAα cat HDR Plasmid (h2)

sc-400262-HDR-2hHomology Directed RepairPuromycin0
(0)

PKAα cat Double Nickase Plasmid (h)

sc-400262-NIChGene KnockoutPuromycin0
(0)

PKAα cat Double Nickase Plasmid (h2)

sc-400262-NIC-2hGene KnockoutPuromycin0
(0)

PKAα cat CRISPR/Cas9 KO Plasmid (m)

sc-422256mGene KnockoutGFP0
(0)

PKAα cat HDR Plasmid (m)

sc-422256-HDRmHomology Directed RepairPuromycin0
(0)

PKAβ cat CRISPR/Cas9 KO Plasmid (h)

sc-400649hGene KnockoutGFP0
(0)

PKAβ cat HDR Plasmid (h)

sc-400649-HDRhHomology Directed RepairPuromycin0
(0)

PKAγ cat CRISPR/Cas9 KO Plasmid (h)

sc-400874hGene KnockoutGFP0
(0)

PKA CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PKA IIα reg CRISPR Activation Plasmid (h)

sc-401080-ACThGene ActivationPuro, Blast, Hygro0
(0)

PKA IIβ reg CRISPR Activation Plasmid (h)

sc-402536-ACThGene ActivationPuro, Blast, Hygro0
(0)

PKAβ cat CRISPR Activation Plasmid (h)

sc-400649-ACThGene ActivationPuro, Blast, Hygro0
(0)

PKAβ cat CRISPR Activation Plasmid (h2)

sc-400649-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PKAγ cat CRISPR Activation Plasmid (h)

sc-400874-ACThGene ActivationPuro, Blast, Hygro0
(0)

PKA siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PKA Iα reg siRNA (h)

sc-39162hGene SilencingN/A
2
(0)

PKA Iα reg shRNA Plasmid (h)

sc-39162-SHhGene SilencingPuromycin
2
(0)

PKA Iα reg shRNA (h) Lentiviral Particles

sc-39162-VhGene SilencingPuromycin
2
(0)

PKA Iα reg siRNA (m)

sc-39163mGene SilencingN/A0
(0)

PKA Iα reg shRNA Plasmid (m)

sc-39163-SHmGene SilencingPuromycin0
(0)

PKA Iα reg shRNA (m) Lentiviral Particles

sc-39163-VmGene SilencingPuromycin0
(0)

PKA Iβ reg siRNA (h)

sc-36238hGene SilencingN/A0
(0)

PKA Iβ reg shRNA Plasmid (h)

sc-36238-SHhGene SilencingPuromycin0
(0)

PKA Iβ reg shRNA (h) Lentiviral Particles

sc-36238-VhGene SilencingPuromycin0
(0)

PKA Iβ reg siRNA (m)

sc-36239mGene SilencingN/A0
(0)

PKA Iβ reg shRNA Plasmid (m)

sc-36239-SHmGene SilencingPuromycin0
(0)

PKA Iβ reg shRNA (m) Lentiviral Particles

sc-36239-VmGene SilencingPuromycin0
(0)

PKA IIα reg siRNA (h)

sc-39164hGene SilencingN/A
1
(0)

PKA IIα reg shRNA Plasmid (h)

sc-39164-SHhGene SilencingPuromycin
1
(0)

PKA IIα reg shRNA (h) Lentiviral Particles

sc-39164-VhGene SilencingPuromycin
1
(0)

PKA IIα reg siRNA (m)

sc-39165mGene SilencingN/A0
(0)

PKA IIα reg shRNA Plasmid (m)

sc-39165-SHmGene SilencingPuromycin0
(0)

PKA IIα reg shRNA (m) Lentiviral Particles

sc-39165-VmGene SilencingPuromycin0
(0)

PKA IIβ reg siRNA (h)

sc-39166hGene SilencingN/A0
(0)

PKA IIβ reg shRNA Plasmid (h)

sc-39166-SHhGene SilencingPuromycin0
(0)

PKA IIβ reg shRNA (h) Lentiviral Particles

sc-39166-VhGene SilencingPuromycin0
(0)

PKA IIβ reg siRNA (m)

sc-39167mGene SilencingN/A0
(0)

PKA IIβ reg shRNA Plasmid (m)

sc-39167-SHmGene SilencingPuromycin0
(0)

PKA IIβ reg shRNA (m) Lentiviral Particles

sc-39167-VmGene SilencingPuromycin0
(0)

PKAα cat siRNA (h)

sc-36240hGene SilencingN/A
15
(0)

PKAα cat shRNA Plasmid (h)

sc-36240-SHhGene SilencingPuromycin
15
(0)

PKAα cat shRNA (h) Lentiviral Particles

sc-36240-VhGene SilencingPuromycin
15
(0)

PKAα cat siRNA (m)

sc-36241mGene SilencingN/A
2
(0)

PKAα cat shRNA Plasmid (m)

sc-36241-SHmGene SilencingPuromycin
2
(0)

PKAα cat shRNA (m) Lentiviral Particles

sc-36241-VmGene SilencingPuromycin
2
(0)

PKAα cat siRNA (r)

sc-156094rGene SilencingN/A
2
(0)

PKAα cat shRNA Plasmid (r)

sc-156094-SHrGene SilencingPuromycin
2
(0)

PKAα cat shRNA (r) Lentiviral Particles

sc-156094-VrGene SilencingPuromycin
2
(0)

PKAβ cat siRNA (h)

sc-39158hGene SilencingN/A
2
(0)

PKAβ cat shRNA Plasmid (h)

sc-39158-SHhGene SilencingPuromycin
2
(0)

PKAβ cat shRNA (h) Lentiviral Particles

sc-39158-VhGene SilencingPuromycin
2
(0)

PKAβ cat siRNA (m)

sc-39160mGene SilencingN/A0
(1)

PKAβ cat shRNA Plasmid (m)

sc-39160-SHmGene SilencingPuromycin0
(1)

PKAβ cat shRNA (m) Lentiviral Particles

sc-39160-VmGene SilencingPuromycin0
(1)

PKAγ cat siRNA (h)

sc-36236hGene SilencingN/A
2
(0)

PKAγ cat shRNA Plasmid (h)

sc-36236-SHhGene SilencingPuromycin
2
(0)

PKAγ cat shRNA (h) Lentiviral Particles

sc-36236-VhGene SilencingPuromycin
2
(0)

PKAγ cat siRNA (m)

sc-36237mGene SilencingN/A0
(0)

PKAγ cat shRNA Plasmid (m)

sc-36237-SHmGene SilencingPuromycin0
(0)

PKAγ cat shRNA (m) Lentiviral Particles

sc-36237-VmGene SilencingPuromycin0
(0)