Date published: 2026-3-14

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Peptide YY Activators

Peptide YY activators include a variety of chemical compounds that indirectly augment the functional activity of Peptide YY through modulation of various signaling pathways and physiological processes, especially those related to appetite control and gastrointestinal motility. Forskolin, for instance, increases intracellular cAMP levels, potentially amplifying the Peptide YY mediated effects on reducing appetite by enhancing relevant cellular signaling pathways. Capsaicin's interaction with sensory neurons suggests a possible enhancement of the Peptide YY's role in gut-brain signaling, thus influencing satiety. Similarly, substances like caffeine and nicotine, known to modulate appetite and feeding behavior, might indirectly affect the pathways regulating or regulated by Peptide YY, altering its functional impact. Oleoylethanolamide, known for its role in lipid metabolism and reducing food intake, along with Epigallocatechin gallate, a compound affecting metabolic rate and fat oxidation, could influence Peptide YY activity through shared pathways in energy homeostasis.

Additionally, compounds like naltrexone, liraglutide, and resveratrol might modulate Peptide YY's activity by influencing overlapping pathways associated with energy balance, appetite, and gut motility. Naltrexone's role in opioid receptor antagonism could affect eating behavior, potentially enhancing Peptide YY's role in appetite suppression. Liraglutide, mimicking GLP-1 effects, might synergistically or additively influence Peptide YY's activity. Resveratrol's impact on insulin sensitivity and fat metabolism offers potential cross-talk with Peptide YY pathways, indirectly modulating its effects. Lastly, Metformin and Pioglitazone, widely used in glucose metabolism management, might also affect Peptide YY indirectly through alterations in nutrient sensing and energy balance, showcasing the diverse and complex nature of potential Peptide YY activators in modulating satiety and gastrointestinal functions without direct interaction. This intricate network of indirect activators underscores the multifaceted roles and regulation of Peptide YY in maintaining energy and digestive homeostasis.

SEE ALSO...

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin increases intracellular cAMP levels, which can enhance the signaling pathways that Peptide YY is involved in, potentially increasing its effect on reducing appetite and slowing gastrointestinal motility.

Capsaicin

404-86-4sc-3577
sc-3577C
sc-3577D
sc-3577A
50 mg
250 mg
500 mg
1 g
$96.00
$160.00
$240.00
$405.00
26
(1)

Capsaicin interacts with sensory neurons that can influence gut-brain signaling, potentially enhancing the satiety effect mediated by Peptide YY.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Caffeine consumption influences metabolic rate and appetite control, possibly affecting Peptide YY activity indirectly through alterations in energy balance and gut motility.

Oleylethanolamide

111-58-0sc-201400
sc-201400A
10 mg
50 mg
$90.00
$194.00
1
(1)

OEA is known to reduce food intake and enhance lipid metabolism, potentially interacting with pathways that Peptide YY also influences, leading to enhanced activity.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

Found in green tea, EGCG can influence metabolic rate and fat oxidation, possibly affecting signaling pathways that modulate Peptide YY's role in energy homeostasis.

Naloxone

465-65-6sc-477809
200 mg
$306.00
5
(0)

As an opioid receptor antagonist, naltrexone might influence feeding behavior and energy balance, indirectly affecting Peptide YY activity.

Liraglutide

204656-20-2sc-507404
1 mg
$220.00
(0)

Liraglutide, a GLP-1 analog, might enhance Peptide YY release or mimic its effects due to the overlapping roles in regulating appetite and glucose homeostasis.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol influences insulin sensitivity and fat metabolism, pathways that Peptide YY may also affect, thus potentially enhancing its activity indirectly.

Dextran

9004-54-0sc-218165
sc-218165A
sc-218165B
sc-218165C
sc-218165D
sc-218165E
10 g
50 g
100 g
250 g
500 g
1 kg
$73.00
$133.00
$245.00
$485.00
$765.00
$1020.00
(0)

Although it's a protein, synthetic leptin or leptin analogs might influence energy balance and appetite control mechanisms that also involve Peptide YY.

Metformin

657-24-9sc-507370
10 mg
$79.00
2
(0)

Metformin influences glucose metabolism and might affect gut hormones including Peptide YY, indirectly influencing its activity.