Peptide YY Antibody (029-01-1): sc-80499

Peptide YY Antibody (029-01-1) is a mouse monoclonal IgG1 antibody that detects human Peptide YY (PYY) by enzyme-linked immunosorbent assay (ELISA). Anti-PYY antibody (029-01-1) is available as a non-conjugated format, providing researchers with a reliable tool for studying PYY. PYY, also known as peptide tyrosine tyrosine, is a secreted protein primarily produced in the gastrointestinal tract, particularly in the L cells of the ileum and colon. PYY plays a crucial role in regulating appetite and gastrointestinal motility, acting as an inhibitor of exocrine pancreatic secretion and influencing both jejunal and colonic motility. PYY′s significance lies in modulating food intake and energy balance, making PYY a key player in metabolic processes and potential therapeutic target for obesity and related disorders. PYY interacts with the Neuropeptide Y-receptor family, which is part of the G protein-coupled receptor superfamily, further underscoring PYY′s importance in neuroendocrine signaling pathways.

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Peptide YY Antibody (029-01-1) References:

1. Ghrelin, peptide YY and their receptors: gene expression in brain from subjects with and without Prader-Willi syndrome.  |  Talebizadeh, Z., et al. 2005. Int J Mol Med. 15: 707-11. PMID: 15754036
2. Peptide YY: a potential therapy for obesity.  |  Renshaw, D. and Batterham, RL. 2005. Curr Drug Targets. 6: 171-9. PMID: 15777187
3. The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway.  |  Abbott, CR., et al. 2005. Brain Res. 1044: 127-31. PMID: 15862798
4. A new molecular form of PYY: structural characterization of human PYY(3-36) and PYY(1-36).  |  Eberlein, GA., et al. 1989. Peptides. 10: 797-803. PMID: 2587421
5. Isolation and primary structure of human peptide YY.  |  Tatemoto, K., et al. 1988. Biochem Biophys Res Commun. 157: 713-7. PMID: 3202875
6. Cloning and structural determination of human peptide YY cDNA and gene.  |  Kohri, K., et al. 1993. Biochim Biophys Acta. 1173: 345-9. PMID: 8318545

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Peptide YY Antibody (029-01-1) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Peptide YY Antibody (029-01-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Peptide YY Antibody (029-01-1) Specifications

Alternate Product Name: Peptide YY

Product Clone Name: 029-01-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Peptide YY

Epitope Species: human

Product Reactivity/Detection: Peptide YY

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Peptide YY Antibody (029-01-1): N/A