Date published: 2026-5-30

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PCDHGA6 Inhibitors

The chemical class denoted as PCDHGA6 Inhibitors is designed to selectively modulate the activity of protocadherin gamma subfamily A member 6 (PCDHGA6). Protocadherins, a family of cell adhesion molecules, play crucial roles in various cellular processes, particularly in the development and maintenance of neural circuits. PCDHGA6, as a member of the protocadherin gamma subfamily, is likely involved in mediating cell-cell interactions that contribute to the intricate wiring of the nervous system. Inhibitors targeting PCDHGA6 operate by interfering with its normal functions, disrupting the complex molecular interactions and signaling pathways in which PCDHGA6 is engaged. This interference may lead to alterations in cell adhesion patterns and could impact cellular communication processes governed by PCDHGA6.

The mechanism of action for PCDHGA6 inhibitors involves their selective binding to PCDHGA6, modulating its activity and potentially influencing downstream cellular processes. These inhibitors serve as valuable tools for researchers seeking to elucidate the specific functions of protocadherins within the broader landscape of cellular biology, especially in the intricate processes of neural development and synaptic connectivity. The study of PCDHGA6 inhibitors, in this theoretical scenario, contributes to our understanding of the regulatory mechanisms that govern cell adhesion and communication, providing insights into the complex molecular processes involved in the formation and maintenance of neuronal networks.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

As a DNA methyltransferase inhibitor, 5-Azacytidine can cause DNA demethylation, potentially affecting PCDHGA6 expression by altering epigenetic marks.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Trichostatin A inhibits histone deacetylases (HDACs), leading to changes in chromatin structure and possibly decreasing PCDHGA6 expression.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$133.00
$275.00
37
(2)

Vorinostat is an HDAC inhibitor, which could lead to altered histone acetylation status and potentially downregulate PCDHGA6 expression.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$131.00
$515.00
2
(1)

RG108 is another DNA methyltransferase inhibitor that could hypothetically reduce PCDHGA6 expression by changing methylation patterns.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

Decitabine is a DNA methyltransferase inhibitor used to induce DNA demethylation, which may influence PCDHGA6 gene expression.

Mocetinostat

726169-73-9sc-364539
sc-364539B
sc-364539A
5 mg
10 mg
50 mg
$214.00
$247.00
$1463.00
2
(1)

Mocetinostat is an HDAC inhibitor that can alter chromatin structure and potentially affect the expression of genes like PCDHGA6.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$90.00
$212.00
24
(2)

Entinostat selectively inhibits class I HDACs, which may result in chromatin remodeling and subsequent downregulation of certain genes, including PCDHGA6.

Panobinostat

404950-80-7sc-208148
10 mg
$200.00
9
(1)

Panobinostat is a potent HDAC inhibitor that might influence the expression of genes by altering the acetylation status of histones.

Romidepsin

128517-07-7sc-364603
sc-364603A
1 mg
5 mg
$218.00
$634.00
1
(1)

Romidepsin is an HDAC inhibitor that can affect gene expression by changing the acetylation state of histones associated with gene regulatory regions.

Ademetionine

29908-03-0sc-278677
sc-278677A
100 mg
1 g
$184.00
$668.00
2
(1)

S-Adenosylmethionine serves as a methyl donor for transmethylation reactions and could indirectly affect the expression of PCDHGA6 by modulating methylation patterns.