Date published: 2025-11-1

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PALD Activators

PALD activators belong to a unique class of chemical agents designed to interact with and modulate the activity of the PALD enzyme. PALD, an acronym that stands for a specific enzyme found within various biological systems, plays a crucial role in a particular biochemical pathway. The activators are typically small molecules that can cross cell membranes and reach the intracellular environment where the PALD enzyme is located. Upon interaction with the PALD enzyme, these activators bind to the enzyme's active site or to an allosteric site, which is a different region of the enzyme that can influence its activity. The binding is typically highly specific, ensuring that the activator affects only the PALD enzyme and not other enzymes or proteins within the cell.

The design of PALD activators is grounded in complex organic chemistry and often requires a deep understanding of the enzyme's structure and the dynamics of its active site. The activators are crafted to fit precisely within the targeted region of the PALD enzyme, often mimicking the natural substrate or interacting with key amino acids that are crucial for the enzyme's catalytic function. By enhancing the enzyme's activity, these molecules alter the rate at which the PALD enzyme catalyzes its specific reaction within the biochemical pathway. The activation process can lead to a cascade of events within the cell, as the enhanced activity of the PALD enzyme can significantly influence the concentrations of various metabolites and intermediates involved in the pathway. The specificity and potency of PALD activators make them a focal point of interest in the realm of biochemical research, providing insights into enzyme regulation and the complex interplay of metabolic processes.

SEE ALSO...

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin activates adenylate cyclase, leading to an increase in cyclic AMP (cAMP) levels, which can enhance PALD activity by cAMP-dependent protein kinase (PKA) signaling pathways.

IBMX

28822-58-4sc-201188
sc-201188B
sc-201188A
200 mg
500 mg
1 g
$159.00
$315.00
$598.00
34
(1)

IBMX is a nonspecific inhibitor of phosphodiesterases, which prevents the breakdown of cAMP and cGMP, indirectly maintaining higher levels of PKA activity that can enhance PALD signaling.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA activates protein kinase C (PKC), which can phosphorylate various substrates, potentially increasing PALD activity as PKC is involved in numerous cellular signaling pathways.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$76.00
$265.00
80
(4)

Ionomycin is a calcium ionophore that increases intracellular calcium levels, possibly leading to the activation of calcium-dependent kinases and phosphatases that modulate PALD's activity.

Isoproterenol Hydrochloride

51-30-9sc-202188
sc-202188A
100 mg
500 mg
$27.00
$37.00
5
(0)

Isoproterenol is a beta-adrenergic agonist leading to the activation of adenylate cyclase and an increase in cAMP levels, which can enhance PALD activity through PKA.

Rolipram

61413-54-5sc-3563
sc-3563A
5 mg
50 mg
$75.00
$212.00
18
(1)

Rolipram is a selective phosphodiesterase 4 inhibitor, increasing cAMP levels in the cells, which can lead to enhanced PALD activity through PKA signaling pathways.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG is a polyphenol that can inhibit various protein kinases, potentially reducing negative regulatory effects on PALD and indirectly enhancing its activity.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

Anisomycin is a protein synthesis inhibitor that activates stress-activated protein kinases (SAPKs), which could lead to the enhancement of PALD activity as part of the stress response pathways.

Dibutyryl-cAMP

16980-89-5sc-201567
sc-201567A
sc-201567B
sc-201567C
20 mg
100 mg
500 mg
10 g
$45.00
$130.00
$480.00
$4450.00
74
(7)

Dibutyryl cAMP is a cell-permeable cAMP analog that activates PKA and can enhance PALD activity through cAMP-dependent signaling pathways.

Okadaic Acid

78111-17-8sc-3513
sc-3513A
sc-3513B
25 µg
100 µg
1 mg
$285.00
$520.00
$1300.00
78
(4)

Okadaic acid is a potent inhibitor of protein phosphatases PP1 and PP2A, leading to increased phosphorylation levels of proteins, which could indirectly enhance PALD activity.