OTTMUSG00000013284 Inhibitors
The inhibition of the protein Gm13667 by the listed chemicals is based on general principles of protein biochemistry and inhibition. These chemicals have been chosen for their ability to interact with and inhibit proteins with specific structural or functional characteristics that Gm13667 might possess. For instance, Phenylmethylsulfonyl fluoride and AEBSF target serine residues in active sites, suggesting that if Gm13667 has serine protease-like activity, these inhibitors would be effective. Similarly, Iodoacetamide and Allicin target cysteine residues, and their effectiveness would depend on the presence of such residues in Gm13667's active site.
Chelating agents like EDTA and O-Phenanthroline have been included due to their ability to inhibit metalloproteins by removing essential metal cofactors, which would be effective if Gm13667 is a metalloprotein. Protease inhibitors like E-64, Pepstatin A, Leupeptin, Bestatin, MG-132, and Lactacystin have been selected based on their specific inhibitory action on different classes of proteases. If Gm13667 falls into one of these classes, such as serine protease, cysteine protease, aspartic protease, aminopeptidase, or proteasome, these inhibitors would impede its function. This approach of selecting chemical inhibitors is based on the potential characteristics of Gm13667, inferred from common protein functionalities. The actual inhibition of Gm13667 by these chemicals would require experimental validation, as these are theoretical selections based on known protein-inhibitor interactions.
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Items 11 to 20 of 20 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AEBSF hydrochloride | 30827-99-7 | sc-202041 sc-202041A sc-202041B sc-202041C sc-202041D sc-202041E | 50 mg 100 mg 5 g 10 g 25 g 100 g | $65.00 $122.00 $428.00 $851.00 $1873.00 $4994.00 | 33 | |
AEBSF is a serine protease inhibitor that would inhibit Gm13667 if it has a serine protease-like mechanism, by covalently modifying the serine residue in the active site. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin inhibits olfactory receptor 1506-like isoform X1 by binding to a site on the receptor, which leads to a change in receptor conformation. This change decreases the receptor′s ability to bind to its natural ligands, thus effectively inhibiting its normal sensory function. | ||||||
Bestatin | 58970-76-6 | sc-202975 | 10 mg | $131.00 | 19 | |
Bestatin, an aminopeptidase inhibitor, could inhibit Gm13667 if it functions as an aminopeptidase, by binding to its active site and preventing substrate access. | ||||||
Thymol | 89-83-8 | sc-215984 sc-215984A | 100 g 500 g | $97.00 $193.00 | 3 | |
Thymol can inhibit olfactory receptor 1506-like isoform X1 by binding to the receptor in a way that alters its conformation and hinders its ability to interact with odorant molecules. This binding prevents the normal activation of the receptor′s signaling pathway. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
MG-132 inhibits proteasomes and calpains. If Gm13667 is a protease of similar classification, MG-132 would inhibit its proteolytic activity. | ||||||
Lactacystin | 133343-34-7 | sc-3575 sc-3575A | 200 µg 1 mg | $188.00 $575.00 | 60 | |
Lactacystin is a specific inhibitor of the proteasome. If Gm13667 is a proteasome-like protein, lactacystin would inhibit its proteolytic activity. | ||||||
o-Phenanthroline monohydrate | 5144-89-8 | sc-202256 sc-202256A | 1 g 25 g | $43.00 $188.00 | 1 | |
O-Phenanthroline chelates metal ions and could inhibit Gm13667 if it is a metalloenzyme, by removing its metal cofactors. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene acts as an inhibitor of olfactory receptor 1506-like isoform X1 by competitively binding to the receptor′s odorant binding site. This binding prevents natural odorants from interacting with the receptor, thereby reducing its signal transduction activity. | ||||||
Isoeugenol | 97-54-1 | sc-250186 sc-250186A | 5 g 100 g | $63.00 $53.00 | ||
Isoeugenol inhibits olfactory receptor 1506-like isoform X1 by interacting with the receptor′s ligand-binding domain and altering its structure. This alteration impairs the receptor′s ability to bind to and respond to odorant molecules, leading to inhibition of its normal function. | ||||||
Allicin | 539-86-6 | sc-202449 sc-202449A | 1 mg 5 mg | $489.00 $1557.00 | 7 | |
Allicin can inhibit thiol-containing enzymes. If Gm13667 contains reactive thiol groups in its active site, allicin would modify these groups and inhibit the protein's function. | ||||||