Date published: 2025-11-22

1-800-457-3801

SCBT Portrait Logo
Seach Input

D-Limonene (CAS 5989-27-5)

5.0(1)
Write a reviewAsk a question

See product citations (3)

Alternate Names:
(+)-Dipentene; (R)-(+)-Limonene
Application:
D-Limonene is which activates UGT and hepatic GST
CAS Number:
5989-27-5
Purity:
≥96%
Molecular Weight:
136.23
Molecular Formula:
C10H16
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

D-Limonene is an organic compound known for its prominent role in the flavor and fragrance industries, as well as in green chemistry applications. It is a monoterpene found in the oils of citrus fruits and is responsible for the characteristic scent of oranges and other citrus species. In research, D-Limonene is studied for its solvent properties, particularly as an eco-friendly alternative to traditional, more hazardous solvents in chemical synthesis and cleaning products. It is also a subject of interest in materials science, where it is used in the formulation of biodegradable polymers and resins. Researchers explore the effectiveness of D-Limonene in solubilizing various substances and its potential use in enhancing the penetration of active compounds in material matrices. Moreover, due to its natural origin and low toxicity, D-Limonene is investigated for its role in the development of sustainable industrial processes.


D-Limonene (CAS 5989-27-5) References

  1. Air oxidation of d-limonene (the citrus solvent) creates potent allergens.  |  Karlberg, AT., et al. 1992. Contact Dermatitis. 26: 332-40. PMID: 1395597
  2. Effect of D-limonene on immune response in BALB/c mice with lymphoma.  |  Del Toro-Arreola, S., et al. 2005. Int Immunopharmacol. 5: 829-38. PMID: 15778119
  3. The presence of alpha 2u-globulin is necessary for d-limonene promotion of male rat kidney tumors.  |  Dietrich, DR. and Swenberg, JA. 1991. Cancer Res. 51: 3512-21. PMID: 1711412
  4. Response of Saccharomyces cerevisiae to D-limonene-induced oxidative stress.  |  Liu, J., et al. 2013. Appl Microbiol Biotechnol. 97: 6467-75. PMID: 23644769
  5. Effects of nisin on the antimicrobial activity of d-limonene and its nanoemulsion.  |  Zhang, Z., et al. 2014. Food Chem. 150: 307-12. PMID: 24360455
  6. d-Limonene-induced male rat-specific nephrotoxicity: evaluation of the association between d-limonene and alpha 2u-globulin.  |  Lehman-McKeeman, LD., et al. 1989. Toxicol Appl Pharmacol. 99: 250-9. PMID: 2472019
  7. Preparation and stabilization of D-limonene Pickering emulsions by cellulose nanocrystals.  |  Wen, C., et al. 2014. Carbohydr Polym. 112: 695-700. PMID: 25129799
  8. The prevention of nitrosomethylurea-induced mammary tumors by d-limonene and orange oil.  |  Maltzman, TH., et al. 1989. Carcinogenesis. 10: 781-3. PMID: 2702727
  9. Review of toxicological assessment of d-limonene, a food and cosmetics additive.  |  Ravichandran, C., et al. 2018. Food Chem Toxicol. 120: 668-680. PMID: 30075315
  10. Anti-carcinogenic activity of d-limonene during the initiation and promotion/progression stages of DMBA-induced rat mammary carcinogenesis.  |  Elson, CE., et al. 1988. Carcinogenesis. 9: 331-2. PMID: 3123086
  11. Bradycardic and Antiarrhythmic Effects of the D-Limonene in Rats.  |  Nascimento, GAD., et al. 2019. Arq Bras Cardiol. 113: 925-932. PMID: 31482987
  12. Inhibition of DMBA-induced mammary cancer by the monoterpene d-limonene.  |  Elegbede, JA., et al. 1984. Carcinogenesis. 5: 661-4. PMID: 6426810
  13. d-limonene exposure to humans by inhalation: uptake, distribution, elimination, and effects on the pulmonary function.  |  Falk-Filipsson, A., et al. 1993. J Toxicol Environ Health. 38: 77-88. PMID: 8421324
  14. Effects of anticarcinogenic monoterpenes on phase II hepatic metabolizing enzymes.  |  Elegbede, JA., et al. 1993. Carcinogenesis. 14: 1221-3. PMID: 8508509
  15. Cancer chemoprevention and therapy by monoterpenes.  |  Gould, MN. 1997. Environ Health Perspect. 105 Suppl 4: 977-9. PMID: 9255590

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Limonene, 100 ml

sc-205283
100 ml
$82.00

D-Limonene, 500 ml

sc-205283A
500 ml
$126.00