Date published: 2025-10-16

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Other Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Crosslinkers for use in various applications. Crosslinkers are pivotal in scientific research as they enable the covalent bonding of molecules to study protein interactions, molecular structures, and biochemical pathways. These reagents facilitate the linking of two or more molecules, such as proteins or nucleic acids, which helps in stabilizing complex structures and understanding the spatial arrangement of biological macromolecules. The Other Crosslinkers category encompasses a diverse array of chemical entities designed to create specific and stable covalent bonds between target molecules under various experimental conditions. These compounds are essential in studying protein-protein interactions, mapping binding sites, and elucidating the architecture of macromolecular complexes. By employing these crosslinkers, researchers can capture transient interactions and stabilize delicate structures for analysis using techniques such as mass spectrometry, X-ray crystallography, and nuclear magnetic resonance (NMR) spectroscopy. Furthermore, crosslinkers are instrumental in the development of new materials, as they are used to modify surface properties, create hydrogels, and improve the mechanical strength of polymers. The versatility and specificity of Other Crosslinkers make them invaluable tools for advancing research in structural biology, biochemistry, and materials science. View detailed information on our available Other Crosslinkers by clicking on the product name.

Items 31 to 40 of 214 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

HBTU

94790-37-1sc-203074
sc-203074A
100 g
250 g
$332.00
$663.00
1
(0)

HBTU is a versatile crosslinker characterized by its unique ability to facilitate amide bond formation through its reactive uronium structure. This compound exhibits rapid reaction kinetics, enabling efficient coupling reactions with amino groups. Its strong electrophilic nature promotes selective interactions, while the presence of a bulky group enhances steric hindrance, allowing for tailored crosslinking density. Additionally, HBTU's solubility in polar solvents aids in uniform distribution within polymer matrices, optimizing network formation.

4-Oxo-2-nonenal

103560-62-9sc-202020
sc-202020A
1 mg
5 mg
$150.00
$720.00
(0)

4-Oxo-2-nonenal is a reactive compound known for its ability to form covalent bonds through Michael addition and nucleophilic attack, particularly with thiols and amines. Its electrophilic carbonyl group facilitates rapid crosslinking, leading to the formation of stable adducts. The compound's unique structure allows for selective interactions, enhancing the mechanical properties of polymer networks. Additionally, its hydrophobic nature influences solubility and distribution in various matrices, promoting effective crosslinking.

Trioxsalen

3902-71-4sc-216017
sc-216017A
1 g
5 g
$71.00
$306.00
(1)

Trioxsalen is a bifunctional compound that exhibits unique crosslinking behavior through its ability to form covalent bonds via photochemical activation. Upon exposure to UV light, it undergoes a cycloaddition reaction, creating stable linkages with nucleophiles such as DNA and proteins. This process is characterized by its specificity and efficiency, allowing for tailored modifications in complex biological systems. The compound's planar structure enhances π-π stacking interactions, influencing the stability and rigidity of the resulting crosslinked networks.

1,4-Bis(acryloyl)piperazine

6342-17-2sc-203424
sc-203424A
5 g
10 g
$150.00
$260.00
(0)

1,4-Bis(acryloyl)piperazine is a versatile crosslinker known for its ability to form robust networks through radical polymerization. Its dual acrylate functionality enables efficient chain propagation and crosslinking, resulting in materials with enhanced mechanical properties. The compound's piperazine moiety introduces flexibility, facilitating unique molecular interactions that improve the resilience of the final polymer matrix. Additionally, its reactivity allows for rapid curing, making it suitable for diverse applications in polymer science.

tert-Butyl trans-17-bromo-4,7,10,13-tetraoxa-15-heptadecenoate

166668-33-3sc-253643
1 g
$200.00
(0)

tert-Butyl trans-17-bromo-4,7,10,13-tetraoxa-15-heptadecenoate serves as an effective crosslinker, characterized by its unique ability to engage in selective halogenation reactions. The presence of multiple ether linkages enhances its solubility and compatibility with various polymer systems, promoting efficient network formation. Its bromo substituent facilitates nucleophilic attack, leading to diverse crosslinking pathways. This compound's structural features contribute to tailored mechanical properties and thermal stability in polymer matrices.

3-(Fmoc-amino)propyl bromide

186663-83-2sc-231374
5 g
$328.00
(0)

3-(Fmoc-amino)propyl bromide acts as a versatile crosslinker, distinguished by its ability to form stable covalent bonds through nucleophilic substitution. The Fmoc group enhances the compound's reactivity and solubility, allowing for efficient integration into polymer networks. Its bromide moiety promotes rapid reaction kinetics, enabling diverse crosslinking strategies. This compound's unique structural attributes facilitate the development of tailored materials with specific mechanical and thermal characteristics.

3-(2-Pyridylthio)propanoic Acid

68617-64-1sc-206596
50 mg
$220.00
(0)

3-(2-Pyridylthio)propanoic Acid serves as an effective crosslinker, characterized by its ability to engage in thiol-disulfide exchange reactions. The pyridylthio group enhances its reactivity, allowing for selective interactions with thiol-containing compounds. This unique feature promotes the formation of robust crosslinked networks, contributing to improved material stability. Its distinct molecular structure facilitates diverse pathways for crosslinking, enabling the design of materials with tailored properties and functionalities.

4-Sulfamoylbenzoic acid

138-41-0sc-238955
5 g
$27.00
(0)

4-Sulfamoylbenzoic acid acts as a versatile crosslinker, distinguished by its sulfonamide group, which enhances hydrogen bonding and electrostatic interactions. This functionality allows for the formation of stable networks through amide linkages, promoting increased mechanical strength and thermal stability in polymer matrices. Its unique molecular architecture enables selective reactivity with various substrates, facilitating the development of materials with customized characteristics and enhanced performance.

2-Fluorobenzaldehyde

446-52-6sc-238049
10 g
$24.00
(0)

2-Fluorobenzaldehyde serves as a distinctive crosslinker, characterized by its electrophilic carbonyl group, which promotes nucleophilic attack from amines and alcohols. This reactivity leads to the formation of imine and acetal linkages, enhancing network formation. The presence of the fluorine atom introduces unique dipole interactions, influencing the polarity and solubility of the resulting materials. Its ability to modulate reaction kinetics allows for tailored processing conditions, optimizing material properties.

4-Bromobutyric acid

2623-87-2sc-238793
10 g
$35.00
(0)

4-Bromobutyric acid acts as a versatile crosslinker, featuring a bromine atom that enhances its reactivity through halogen bonding. This property facilitates interactions with nucleophiles, leading to the formation of stable covalent bonds. The carboxylic acid group enables acid-catalyzed reactions, promoting efficient crosslinking pathways. Additionally, its moderate hydrophilicity influences the solubility and compatibility of polymer matrices, allowing for customized material characteristics.