Date published: 2025-12-13

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Other Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Crosslinkers for use in various applications. Crosslinkers are pivotal in scientific research as they enable the covalent bonding of molecules to study protein interactions, molecular structures, and biochemical pathways. These reagents facilitate the linking of two or more molecules, such as proteins or nucleic acids, which helps in stabilizing complex structures and understanding the spatial arrangement of biological macromolecules. The Other Crosslinkers category encompasses a diverse array of chemical entities designed to create specific and stable covalent bonds between target molecules under various experimental conditions. These compounds are essential in studying protein-protein interactions, mapping binding sites, and elucidating the architecture of macromolecular complexes. By employing these crosslinkers, researchers can capture transient interactions and stabilize delicate structures for analysis using techniques such as mass spectrometry, X-ray crystallography, and nuclear magnetic resonance (NMR) spectroscopy. Furthermore, crosslinkers are instrumental in the development of new materials, as they are used to modify surface properties, create hydrogels, and improve the mechanical strength of polymers. The versatility and specificity of Other Crosslinkers make them invaluable tools for advancing research in structural biology, biochemistry, and materials science. View detailed information on our available Other Crosslinkers by clicking on the product name.

Items 21 to 30 of 213 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

3-(Boc-amino)propyl bromide

83948-53-2sc-231352
500 mg
$71.00
(0)

3-(Boc-amino)propyl bromide functions as a versatile crosslinker, characterized by its Boc-protected amine group that enhances nucleophilicity. This compound engages in nucleophilic substitution reactions, allowing for the formation of stable covalent bonds with various substrates. Its unique reactivity profile enables tailored crosslinking pathways, resulting in materials with improved mechanical properties and structural integrity. The presence of the bromide enhances its compatibility with diverse functional groups, broadening its application potential.

N,N′-(1,2-Dihydroxyethylene)bis-acrylamide

868-63-3sc-215503
sc-215503A
5 g
25 g
$186.00
$643.00
(0)

N,N'-(1,2-Dihydroxyethylene)bis-acrylamide serves as an effective crosslinker, distinguished by its dual hydroxyl groups that facilitate hydrogen bonding and enhance network formation. This compound exhibits rapid polymerization kinetics, promoting efficient crosslinking under mild conditions. Its ability to form stable, three-dimensional structures contributes to the mechanical strength and thermal stability of the resulting materials, making it a valuable component in various polymer systems.

6-Mercapto-1-hexanol

1633-78-9sc-252298
sc-252298A
5 ml
25 ml
$87.00
$293.00
(1)

6-Mercapto-1-hexanol acts as a versatile crosslinker, characterized by its thiol functional group that enables robust thiol-disulfide exchange reactions. This compound promotes unique molecular interactions, enhancing network density and elasticity in polymer matrices. Its reactivity with various electrophiles allows for tailored modifications, while its hydrophilic nature aids in solubility and dispersion in aqueous environments, influencing the physical properties of the final materials.

N-Z-1,5-pentanediamine hydrochloride

18807-74-4sc-253132
500 mg
$106.00
(0)

N-Z-1,5-pentanediamine hydrochloride serves as an effective crosslinker, distinguished by its primary amine groups that facilitate strong hydrogen bonding and ionic interactions. This compound enhances the structural integrity of polymer networks through its ability to form stable linkages, promoting increased thermal stability and mechanical strength. Its unique reactivity with carboxylic acids and isocyanates allows for diverse functionalization, optimizing material properties for specific applications.

4-Maleimidobutyric Acid

57078-98-5sc-210100
sc-210100A
sc-210100B
sc-210100C
sc-210100D
1 g
10 g
50 g
100 g
500 g
$290.00
$1850.00
$3200.00
$5200.00
$16500.00
2
(0)

4-Maleimidobutyric Acid is a versatile crosslinker characterized by its maleimide functional group, which enables selective thiol-reactive chemistry. This compound promotes the formation of covalent bonds through Michael addition reactions, enhancing the stability and resilience of polymer matrices. Its unique ability to create crosslinks under mild conditions allows for tailored network architectures, influencing the mechanical properties and responsiveness of the resulting materials.

N,N′-Disuccinimidyl carbonate

74124-79-1sc-253161
5 g
$93.00
(0)

N,N'-Disuccinimidyl carbonate is a highly reactive crosslinker known for its ability to facilitate the formation of stable amide bonds through its carbonate moiety. This compound exhibits rapid reaction kinetics, allowing for efficient coupling with nucleophiles, particularly amines. Its unique structure promotes the formation of crosslinked networks that enhance the mechanical integrity of materials. Additionally, it can create diverse architectures, influencing the physical properties of the final products.

1-Azido-3,6,9-trioxaundecane-11-ol

86770-67-4sc-208605
500 mg
$380.00
(1)

1-Azido-3,6,9-trioxaundecane-11-ol is a versatile crosslinker characterized by its azide functional group, which enables unique click chemistry reactions. This compound exhibits selective reactivity with alkynes, facilitating the formation of stable triazole linkages. Its ether segments contribute to solubility and flexibility, enhancing the formation of robust polymer networks. The compound's ability to engage in multiple reaction pathways allows for tailored material properties and diverse structural configurations.

5-(3-Iodopropoxy)-2-nitrobenzyl alcohol

185994-27-8sc-317521
sc-317521A
250 mg
1 g
$150.00
$412.00
(0)

5-(3-Iodopropoxy)-2-nitrobenzyl alcohol serves as a distinctive crosslinker, featuring a nitro group that enhances electron-withdrawing capabilities, promoting nucleophilic attack in polymerization processes. The iodine atom introduces unique halogen bonding interactions, which can influence the physical properties of the resulting materials. Its propoxy chain contributes to hydrophobicity, affecting solubility and compatibility in various matrices, while enabling diverse crosslinking strategies for tailored network architectures.

2-(Fmoc-amino)ethyl bromide

340187-12-4sc-237871
1 g
$52.00
(0)

2-(Fmoc-amino)ethyl bromide acts as a versatile crosslinker, characterized by its Fmoc (9-fluorenylmethoxycarbonyl) protecting group that facilitates selective reactions. The bromide moiety enhances reactivity, allowing for efficient nucleophilic substitution. Its unique structure promotes specific interactions with amines, enabling the formation of stable linkages in polymer networks. Additionally, the presence of the aromatic Fmoc group contributes to the material's rigidity and thermal stability, influencing the overall mechanical properties of the crosslinked systems.

N-(6-Hydroxyhexyl)trifluoroacetamide

40248-34-8sc-253075
1 g
$47.00
(0)

N-(6-Hydroxyhexyl)trifluoroacetamide serves as an effective crosslinker, distinguished by its trifluoroacetamide group, which enhances reactivity through strong electrophilic characteristics. The hydroxyl group facilitates hydrogen bonding, promoting robust interactions with various nucleophiles. This compound exhibits unique reaction kinetics, allowing for rapid crosslinking under mild conditions. Its flexible hydrocarbon chain contributes to the overall elasticity and resilience of the resulting polymer networks, enhancing their mechanical performance.