Date published: 2025-10-16

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Other Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Crosslinkers for use in various applications. Crosslinkers are pivotal in scientific research as they enable the covalent bonding of molecules to study protein interactions, molecular structures, and biochemical pathways. These reagents facilitate the linking of two or more molecules, such as proteins or nucleic acids, which helps in stabilizing complex structures and understanding the spatial arrangement of biological macromolecules. The Other Crosslinkers category encompasses a diverse array of chemical entities designed to create specific and stable covalent bonds between target molecules under various experimental conditions. These compounds are essential in studying protein-protein interactions, mapping binding sites, and elucidating the architecture of macromolecular complexes. By employing these crosslinkers, researchers can capture transient interactions and stabilize delicate structures for analysis using techniques such as mass spectrometry, X-ray crystallography, and nuclear magnetic resonance (NMR) spectroscopy. Furthermore, crosslinkers are instrumental in the development of new materials, as they are used to modify surface properties, create hydrogels, and improve the mechanical strength of polymers. The versatility and specificity of Other Crosslinkers make them invaluable tools for advancing research in structural biology, biochemistry, and materials science. View detailed information on our available Other Crosslinkers by clicking on the product name.

Items 11 to 20 of 214 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

N-Succinimidyl Myristate

69888-86-4sc-215477A
sc-215477
sc-215477B
sc-215477C
sc-215477D
500 mg
1 g
2 g
5 g
10 g
$408.00
$587.00
$1061.00
$2336.00
$4080.00
1
(1)

N-Succinimidyl Myristate serves as a potent crosslinker, characterized by its ability to form stable amide bonds through its reactive succinimidyl group. This compound exhibits a unique hydrophobic tail that enhances membrane interaction and promotes the formation of lipid bilayers. Its reactivity is influenced by the steric and electronic properties of the myristate chain, allowing for controlled crosslinking kinetics and tailored molecular architectures in various experimental setups.

4-Hydroxybenzyl alcohol

623-05-2sc-238868
10 g
$46.00
1
(0)

4-Hydroxybenzyl alcohol functions as an effective crosslinker, distinguished by its ability to engage in hydrogen bonding and π-π stacking interactions due to its aromatic structure. This compound facilitates the formation of robust networks through its hydroxyl group, which can participate in various condensation reactions. Its unique reactivity profile allows for selective crosslinking under mild conditions, enabling the development of tailored polymeric materials with enhanced mechanical properties and thermal stability.

tert-Butyl 4-hydroxybutyrate

59854-12-5sc-258207
500 mg
$267.00
(0)

tert-Butyl 4-hydroxybutyrate serves as a versatile crosslinker, characterized by its ability to form ester linkages that enhance polymer network integrity. Its branched tert-butyl group contributes to steric hindrance, influencing reaction kinetics and promoting selective crosslinking. The compound's hydroxyl functionality enables strong intermolecular interactions, facilitating the formation of durable, thermally stable materials. This unique behavior allows for the customization of polymer properties in various applications.

Suberic acid bis(N-hydroxysuccinimide ester)

68528-80-3sc-253611
sc-253611A
500 mg
1 g
$107.00
$224.00
(0)

Suberic acid bis(N-hydroxysuccinimide ester) acts as an effective crosslinker, distinguished by its dual reactive sites that facilitate efficient conjugation with amines. The presence of the N-hydroxysuccinimide moiety enhances the reactivity and selectivity of the ester groups, promoting rapid crosslinking under mild conditions. This compound's unique structure allows for the formation of robust networks, contributing to improved mechanical properties and stability in diverse polymer systems.

MTSEA Biotin

162758-04-5sc-221960
10 mg
$209.00
(1)

MTSEA Biotin is a versatile crosslinker characterized by its ability to selectively modify thiol groups, enabling the formation of stable thioether bonds. Its biotin moiety enhances affinity for streptavidin, facilitating targeted interactions. The compound exhibits rapid reaction kinetics, allowing for efficient conjugation in various environments. Its unique structure promotes specific molecular interactions, making it a valuable tool for probing protein dynamics and interactions in complex biological systems.

4-[4-(1-Hydroxyethyl)-2-methoxy-5-nitrophenoxy]butyric acid

175281-76-2sc-238751
1 g
$332.00
(1)

4-[4-(1-Hydroxyethyl)-2-methoxy-5-nitrophenoxy]butyric acid serves as a distinctive crosslinker, exhibiting unique reactivity due to its nitrophenoxy group, which can engage in electrophilic aromatic substitution. This compound demonstrates a propensity for forming stable ester linkages, enhancing polymer network integrity. Its hydrophilic nature influences solubility and dispersion in various media, while the hydroxyethyl group contributes to hydrogen bonding, promoting specific molecular interactions in crosslinking applications.

Glutaraldehyde solution, 50% w/w

111-30-8sc-207716
10 ml
$55.00
1
(1)

Glutaraldehyde solution, at 50% w/w, acts as a versatile crosslinker, characterized by its ability to form covalent bonds through its aldehyde groups. This compound facilitates rapid crosslinking reactions, leading to the formation of robust networks. Its reactivity is enhanced in aqueous environments, where it can engage in nucleophilic addition with amines and alcohols. The resulting crosslinked structures exhibit improved mechanical properties and thermal stability, making it suitable for diverse applications.

N,N′,N′′-Triacetylchitotriose

38864-21-0sc-222016
sc-222016A
10 mg
50 mg
$265.00
$1022.00
2
(1)

N,N',N''-Triacetylchitotriose serves as an effective crosslinker, distinguished by its ability to engage in hydrogen bonding and hydrophobic interactions. This compound promotes the formation of intricate networks through its acetylated amine groups, enhancing structural integrity. Its unique reactivity allows for selective crosslinking under mild conditions, facilitating controlled polymerization pathways. The resulting materials exhibit enhanced elasticity and moisture retention, showcasing its potential in various applications.

(Boc-aminooxy)acetic Acid

42989-85-5sc-212986
1 g
$70.00
(0)

(Boc-aminooxy)acetic Acid functions as a versatile crosslinker, characterized by its ability to form stable covalent bonds through its aminooxy group. This compound facilitates the formation of dynamic networks via oxime linkages, enabling tailored material properties. Its reactivity is influenced by pH, allowing for selective crosslinking in diverse environments. The resulting structures exhibit improved mechanical strength and thermal stability, making them suitable for innovative material design.

(S)-2-Pyridylthio Cysteamine Hydrochloride

83578-21-6sc-220057
100 mg
$337.00
(0)

(S)-2-Pyridylthio Cysteamine Hydrochloride serves as a distinctive crosslinker, notable for its thiol and pyridine functionalities that enable unique molecular interactions. Its reactivity is enhanced by the presence of the pyridyl group, promoting selective thiol-disulfide exchange reactions. This compound exhibits rapid reaction kinetics, facilitating the formation of robust networks. The resulting crosslinked structures demonstrate enhanced resilience and adaptability, making them ideal for advanced material applications.