Date published: 2025-10-15

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Other Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Crosslinkers for use in various applications. Crosslinkers are pivotal in scientific research as they enable the covalent bonding of molecules to study protein interactions, molecular structures, and biochemical pathways. These reagents facilitate the linking of two or more molecules, such as proteins or nucleic acids, which helps in stabilizing complex structures and understanding the spatial arrangement of biological macromolecules. The Other Crosslinkers category encompasses a diverse array of chemical entities designed to create specific and stable covalent bonds between target molecules under various experimental conditions. These compounds are essential in studying protein-protein interactions, mapping binding sites, and elucidating the architecture of macromolecular complexes. By employing these crosslinkers, researchers can capture transient interactions and stabilize delicate structures for analysis using techniques such as mass spectrometry, X-ray crystallography, and nuclear magnetic resonance (NMR) spectroscopy. Furthermore, crosslinkers are instrumental in the development of new materials, as they are used to modify surface properties, create hydrogels, and improve the mechanical strength of polymers. The versatility and specificity of Other Crosslinkers make them invaluable tools for advancing research in structural biology, biochemistry, and materials science. View detailed information on our available Other Crosslinkers by clicking on the product name.

Items 1 to 10 of 214 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

N-Boc-1,4-butanediamine

68076-36-8sc-253099
1 ml
$104.00
(1)

N-Boc-1,4-butanediamine serves as a versatile crosslinker, exhibiting unique reactivity due to its protected amine groups. Its structure facilitates the formation of stable covalent bonds through nucleophilic attack, enabling robust network formation in polymer matrices. The steric hindrance from the Boc group enhances selectivity in crosslinking reactions, while its bifunctional nature allows for diverse coupling strategies. This compound's ability to modulate reaction kinetics makes it a valuable tool in material science.

Glutaraldehyde solution, 70% w/w

111-30-8sc-257558
10 ml
$46.00
1
(1)

Glutaraldehyde solution, at 70% w/w, acts as a potent crosslinker through its dialdehyde functionality, enabling rapid formation of covalent bonds with nucleophilic sites in proteins and polymers. Its reactivity is characterized by the formation of stable imine linkages, which enhances structural integrity. The solution's low viscosity facilitates even distribution in formulations, while its ability to crosslink multiple sites simultaneously allows for tailored network architectures, optimizing mechanical properties and stability.

Erbstatin Analog

63177-57-1sc-200511
sc-200511A
5 mg
25 mg
$83.00
$305.00
4
(1)

Erbstatin Analog functions as a versatile crosslinker, exhibiting unique reactivity through its specific interactions with amino acid side chains. Its structure promotes selective binding, leading to the formation of robust covalent linkages that enhance the stability of complex biomolecular networks. The compound's kinetic profile allows for controlled reaction rates, enabling precise manipulation of crosslink density. Additionally, its solubility characteristics facilitate uniform dispersion in various matrices, promoting consistent crosslinking throughout.

N-Alloc-ethylenediamine hydrochloride

sc-301276
sc-301276A
1 g
5 g
$90.00
$413.00
(0)

N-Alloc-ethylenediamine hydrochloride serves as an effective crosslinker, characterized by its ability to engage in dynamic interactions with functional groups in polymers. Its unique structure allows for the formation of stable, multi-point linkages, enhancing the mechanical properties of the resulting materials. The compound's reactivity is influenced by its protonation state, which can be finely tuned to optimize reaction conditions. Furthermore, its compatibility with diverse substrates ensures versatile application in crosslinking processes.

2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethyl Bromide

165963-71-3sc-208969C
sc-208969
sc-208969A
sc-208969B
100 mg
250 mg
500 mg
1 g
$240.00
$571.00
$978.00
$1836.00
(1)

2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethyl Bromide functions as a versatile crosslinker, exhibiting a unique ability to form robust covalent bonds through its bromide leaving group. This compound facilitates rapid reaction kinetics, enabling efficient crosslinking under mild conditions. Its t-Boc protective group enhances solubility and stability, allowing for selective reactions. The ethoxy chains contribute to its flexibility, promoting diverse interactions with various polymeric systems, ultimately improving material resilience and performance.

Biotinamidohexanoyl-6-aminohexanoic acid N-hydroxysuccinimide ester

89889-52-1sc-281516
10 mg
$53.00
(1)

Biotinamidohexanoyl-6-aminohexanoic acid N-hydroxysuccinimide ester serves as a specialized crosslinker, characterized by its ability to engage in selective amide bond formation. The N-hydroxysuccinimide moiety enhances reactivity, facilitating efficient coupling with primary amines. Its biotinylated structure promotes specific binding interactions, enabling targeted crosslinking in complex biomolecular environments. This compound's unique design allows for tailored modifications, enhancing the versatility of polymer networks.

N,N′-Bis(acryloyl)cystamine

60984-57-8sc-215506
5 g
$410.00
(1)

N,N'-Bis(acryloyl)cystamine is a versatile crosslinker known for its unique ability to form disulfide bonds, which can be selectively cleaved under reducing conditions. This property allows for dynamic crosslinking in polymer networks, enabling reversible modifications. The presence of acrylamide groups facilitates rapid polymerization through free radical mechanisms, enhancing reaction kinetics. Its dual functionality promotes diverse interactions, making it suitable for creating complex, responsive materials.

Glutaraldehyde solution, 25% w/w

111-30-8sc-300764A
sc-300764
sc-300764B
10 ml
100 ml
1 L
$20.00
$51.00
$180.00
1
(1)

Glutaraldehyde solution, at 25% w/w, is a potent crosslinker characterized by its ability to form stable covalent bonds with amine groups, leading to the creation of robust networks. Its reactivity is influenced by the presence of aldehyde functional groups, which engage in nucleophilic addition reactions. This results in a rapid crosslinking process, enhancing the mechanical properties of polymers. Additionally, its low viscosity allows for easy handling and uniform distribution in various formulations.

N-Boc- 2,2′-(ethylenedioxy)diethylamine

153086-78-3sc-250447
1 g
$152.00
(1)

N-Boc-2,2'-(ethylenedioxy)diethylamine serves as an effective crosslinker, notable for its unique ability to facilitate dynamic covalent bonding through its ethylenedioxy moiety. This structure promotes enhanced molecular interactions, allowing for tailored network formation. Its reactivity is modulated by the Boc protecting group, which can be selectively removed, enabling controlled crosslinking kinetics. The compound's solubility and compatibility with diverse substrates further enhance its utility in polymer science.

2-[2-(2-Azidoethoxy)ethoxy]ethanol

86520-52-7sc-206350
sc-206350A
500 mg
1 g
$238.00
$390.00
(1)

2-[2-(2-Azidoethoxy)ethoxy]ethanol functions as a versatile crosslinker, distinguished by its azide group that enables click chemistry reactions. This feature allows for rapid and selective bonding with alkyne-functionalized partners, promoting efficient network formation. The compound's ether linkages enhance solubility and flexibility, facilitating unique molecular interactions. Its reactivity can be finely tuned, making it suitable for diverse applications in material science and polymer engineering.