Date published: 2025-12-13

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Other Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Crosslinkers for use in various applications. Crosslinkers are pivotal in scientific research as they enable the covalent bonding of molecules to study protein interactions, molecular structures, and biochemical pathways. These reagents facilitate the linking of two or more molecules, such as proteins or nucleic acids, which helps in stabilizing complex structures and understanding the spatial arrangement of biological macromolecules. The Other Crosslinkers category encompasses a diverse array of chemical entities designed to create specific and stable covalent bonds between target molecules under various experimental conditions. These compounds are essential in studying protein-protein interactions, mapping binding sites, and elucidating the architecture of macromolecular complexes. By employing these crosslinkers, researchers can capture transient interactions and stabilize delicate structures for analysis using techniques such as mass spectrometry, X-ray crystallography, and nuclear magnetic resonance (NMR) spectroscopy. Furthermore, crosslinkers are instrumental in the development of new materials, as they are used to modify surface properties, create hydrogels, and improve the mechanical strength of polymers. The versatility and specificity of Other Crosslinkers make them invaluable tools for advancing research in structural biology, biochemistry, and materials science. View detailed information on our available Other Crosslinkers by clicking on the product name.

Items 41 to 50 of 213 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Mitomycin A

4055-39-4sc-218857
sc-218857A
sc-218857B
sc-218857C
sc-218857D
sc-218857E
sc-218857F
2.5 mg
5 mg
10 mg
50 mg
100 mg
500 mg
1 g
$350.00
$600.00
$1100.00
$4850.00
$8210.00
$34072.00
$64569.00
1
(1)

Mitomycin A serves as a potent crosslinker, characterized by its unique ability to form interstrand crosslinks in DNA through alkylation. This compound exhibits selective reactivity with nucleophilic sites, particularly in guanine bases, leading to the disruption of normal cellular processes. Its distinct reaction kinetics allow for a controlled release of reactive species, enhancing its effectiveness in creating complex molecular networks. The compound's hydrophobic nature also influences its interaction with various substrates, affecting solubility and material properties.

3-Maleimidopropionic acid

7423-55-4sc-216479
1 g
$330.00
(1)

3-Maleimidopropionic acid is a versatile crosslinker known for its ability to form stable thioether bonds with thiol-containing molecules. Its unique reactivity stems from the maleimide group, which selectively reacts with free thiols under mild conditions, facilitating the formation of covalent linkages. This compound exhibits rapid reaction kinetics, allowing for efficient crosslinking in various environments. Additionally, its water solubility enhances compatibility with diverse biological and synthetic systems, making it a valuable tool in material science.

4-Mercapto-1-butanol

14970-83-3sc-238878
sc-238878A
sc-238878B
1 g
10 g
75 g
$176.00
$803.00
$3015.00
(0)

4-Mercapto-1-butanol serves as an effective crosslinker, characterized by its thiol functional group that readily engages in nucleophilic reactions. This compound exhibits unique reactivity with electrophiles, enabling the formation of robust disulfide bonds and enhancing network formation in polymer matrices. Its ability to participate in thiol-ene click chemistry allows for precise control over crosslink density, while its moderate hydrophilicity aids in compatibility with various substrates, promoting diverse applications in material synthesis.

4-(Diphenylhydroxymethyl)benzoic acid

19672-49-2sc-238740
1 g
$147.00
(0)

4-(Diphenylhydroxymethyl)benzoic acid functions as a versatile crosslinker, distinguished by its ability to form hydrogen bonds and π-π stacking interactions due to its aromatic structure. This compound facilitates the creation of stable networks through its carboxylic acid group, which can engage in esterification and amide bond formation. Its unique steric hindrance and electronic properties influence reaction kinetics, allowing for tailored crosslinking in diverse polymer systems.

4-(2-Bromopropionyl)phenoxyacetic acid

33254-93-2sc-252078
500 mg
$719.00
(0)

4-(2-Bromopropionyl)phenoxyacetic acid serves as an effective crosslinker, characterized by its reactivity through the bromopropionyl moiety, which enhances electrophilic interactions. This compound promotes covalent bonding via acylation, enabling the formation of robust polymer networks. Its unique structure allows for selective reactivity, influencing the kinetics of crosslinking processes. Additionally, the phenoxy group contributes to solubility and compatibility with various substrates, enhancing material properties.

N-Acetyl-L-tyrosine ethyl ester monohydrate

36546-50-6sc-269703
5 g
$77.00
(0)

N-Acetyl-L-tyrosine ethyl ester monohydrate acts as a versatile crosslinker, distinguished by its ability to engage in hydrogen bonding and π-π stacking interactions due to the aromatic tyrosine component. This compound facilitates the formation of stable networks through esterification reactions, promoting enhanced mechanical properties. Its hydrophilic nature, derived from the acetyl and ethyl groups, improves solubility in polar solvents, allowing for tailored material characteristics in diverse applications.

Dimethyl 3,3′-dithiopropionimidate dihydrochloride

38285-78-8sc-252733
100 mg
$86.00
(0)

Dimethyl 3,3'-dithiopropionimidate dihydrochloride serves as a unique crosslinker, characterized by its ability to form disulfide bonds, which significantly enhance the structural integrity of polymer matrices. Its dithiol functionality promotes thiol-ene click reactions, enabling rapid crosslinking under mild conditions. The compound's dual hydrochloride form enhances solubility in aqueous environments, facilitating uniform distribution in polymer systems and enabling precise control over network density and mechanical properties.

Nimustine hydrochloride

55661-38-6sc-202732
sc-202732A
250 mg
1 g
$80.00
$150.00
1
(0)

Nimustine hydrochloride acts as a distinctive crosslinker, exhibiting a unique reactivity profile due to its electrophilic nature. It engages in selective covalent bonding with nucleophilic sites, leading to the formation of stable crosslinked networks. The compound's ability to facilitate dynamic covalent interactions allows for tunable reaction kinetics, which can be finely adjusted based on environmental conditions. Its solubility characteristics further promote effective integration into various polymer systems, enhancing overall material performance.

11-Maleimidoundecanoic Acid

57079-01-3sc-357488
sc-357488A
sc-357488B
sc-357488C
100 mg
250 mg
500 mg
1 g
$199.00
$352.00
$571.00
$765.00
(0)

11-Maleimidoundecanoic Acid serves as a versatile crosslinker, characterized by its maleimide functional group that enables specific thiol-reactive interactions. This compound promotes the formation of robust covalent bonds through Michael addition reactions, allowing for precise control over crosslink density. Its hydrophobic tail enhances compatibility with various polymer matrices, while its unique reactivity facilitates the development of tailored materials with desirable mechanical properties and stability.

N-[4-(-Carboxycyclohexylmethyl)]maleimide

64987-82-2sc-212048
20 mg
$150.00
(0)

N-[4-(-Carboxycyclohexylmethyl)]maleimide is a specialized crosslinker distinguished by its unique cyclohexylmethyl moiety, which enhances steric hindrance and influences reaction kinetics. This compound engages in selective Michael addition with thiols, promoting stable covalent linkages. Its carboxylic acid group introduces additional functionality, allowing for pH-responsive behavior and improved solubility in polar environments, making it suitable for diverse polymeric applications.