OR10A3 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
Verapamil is an L-type calcium channel blocker that can decrease intracellular calcium levels. Low calcium levels could inhibit OR10A3 indirectly by disrupting the calcium-dependent activation process required for proper receptor function. | ||||||
Diltiazem | 42399-41-7 | sc-204726 sc-204726A | 1 g 5 g | $209.00 $464.00 | 4 | |
Diltiazem, another calcium channel blocker, specifically targets cardiac tissue but can also decrease intracellular calcium in other cell types. This reduction might inhibit OR10A3 activation in olfactory sensory neurons by reducing receptor sensitivity to odorant molecules. | ||||||
Quinine | 130-95-0 | sc-212616 sc-212616A sc-212616B sc-212616C sc-212616D | 1 g 5 g 10 g 25 g 50 g | $79.00 $104.00 $166.00 $354.00 $572.00 | 1 | |
Quinine is a known inhibitor of cyclic nucleotide-gated (CNG) channels, which play a critical role in olfactory signal transduction. Inhibition of CNG channels could prevent the activation of the OR10A3 receptor by blocking the necessary ion flow. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine can raise the pH of acidic vesicles within cells and potentially interfere with G-protein coupled receptor (GPCR) function, including OR10A3, by impeding the receptor's ability to interact with its signaling cascade. | ||||||
Carbachol | 51-83-2 | sc-202092 sc-202092A sc-202092C sc-202092D sc-202092B sc-202092E | 1 g 10 g 25 g 50 g 100 g 250 g | $122.00 $281.00 $388.00 $683.00 $1428.00 $3060.00 | 12 | |
Carbachol is a cholinergic agonist that can activate muscarinic receptors, leading to increased intracellular calcium. This rise in calcium levels could subsequently inhibit OR10A3 through a negative feedback mechanism that desensitizes olfactory receptors. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $56.00 $183.00 $352.00 | 1 | |
Cadmium chloride can inhibit calcium channels and calcium-dependent enzymes. By reducing calcium signaling, it may indirectly inhibit OR10A3 activity in olfactory sensory neurons. | ||||||
Ibuprofen | 15687-27-1 | sc-200534 sc-200534A | 1 g 5 g | $53.00 $88.00 | 6 | |
Ibuprofen can inhibit cyclooxygenase enzymes (COX), which are part of the inflammatory response pathway. By reducing prostaglandin synthesis, it can potentially interfere with OR10A3 function, as prostaglandins can modulate GPCR activity. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc gluconate provides zinc ions, which can interfere with GPCR signaling and ion channel function. Excess zinc can disrupt olfactory receptor function, including OR10A3, by altering receptor conformation or signaling. | ||||||
Sodium azide | 26628-22-8 | sc-208393 sc-208393B sc-208393C sc-208393D sc-208393A | 25 g 250 g 1 kg 2.5 kg 100 g | $43.00 $155.00 $393.00 $862.00 $90.00 | 8 | |
Sodium azide inhibits cytochrome c oxidase in the mitochondrial electron transport chain, leading to decreased ATP production. Low ATP levels can impair the phosphorylation-dependent processes required for OR10A3 receptor activation and signaling. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $105.00 $299.00 $474.00 | 15 | |
Gö 6983 is a protein kinase C (PKC) inhibitor. PKC is involved in phosphorylation events that regulate GPCR function, including OR10A3. Inhibition of PKC can decrease OR10A3 receptor phosphorylation, leading to reduced receptor activity. | ||||||