OCR1 Inhibitors
OCR1 inhibitors constitute a diverse class of compounds that modulate cellular processes associated with OCR1. Sodium orthovanadate inhibits tyrosine phosphatases, preventing the dephosphorylation of proteins and potentially sustaining activation of signaling pathways linked to OCR1 functions. Rapamycin inhibits mTOR, influencing cell growth and proliferation and indirectly modulating OCR1-related pathways through downstream signaling cascades.
NSC 23766 inhibits Rac1, affecting cytoskeletal dynamics, while Wortmannin inhibits PI3-kinases, disrupting the PI3K/Akt pathway and impacting OCR1-related cellular processes. Y-27632 inhibits ROCK, influencing cellular morphology and motility, and SU6656 inhibits Src family kinases, affecting cell growth and motility, both potentially influencing OCR1 through indirect pathways.
A769662, an AMPK activator, influences cellular energy metabolism, PD 98059 inhibits MEK1 in the MAPK/ERK pathway, and LY294002 inhibits PI3-kinases, both disrupting downstream signaling cascades associated with OCR1 functions. SB203580 selectively inhibits p38 MAPK, while BAY 11-7082 inhibits NF-κB activation, impacting gene expression linked to OCR1 functions. JNK Inhibitor II targets c-Jun N-terminal kinases, affecting the MAPK pathway and potentially influencing OCR1-related cellular processes. Collectively, these inhibitors provide insights into the molecular pathways regulated by OCR1.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $49.00 $57.00 $187.00 | 142 | |
Sodium orthovanadate inhibits tyrosine phosphatases, potentially influencing OCR1 through modulation of phosphorylation events. This compound can act as an indirect activator by preventing dephosphorylation, leading to sustained activation of signaling pathways associated with OCR1 functions. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, a kinase involved in cell growth and proliferation. Inhibition of mTOR can influence downstream pathways, potentially impacting OCR1-related cellular processes. Rapamycin may act as an indirect activator by modulating signaling cascades that intersect with mTOR-dependent pathways associated with OCR1 functions. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin inhibits PI3-kinases, impacting the PI3K/Akt pathway. Inhibition of PI3-kinases can influence downstream signaling cascades, potentially modulating OCR1-related cellular processes. Wortmannin may act as an indirect activator by disrupting PI3K/Akt-mediated events that intersect with pathways associated with OCR1 functions. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 inhibits ROCK (Rho-associated protein kinase), a regulator of cytoskeletal dynamics. Inhibition of ROCK can affect cellular morphology and motility, potentially influencing OCR1-related processes. Y-27632 may act as an indirect activator by preventing ROCK-mediated signaling events that intersect with pathways associated with OCR1 functions. | ||||||
SU6656 | 330161-87-0 | sc-203286 sc-203286A | 1 mg 5 mg | $57.00 $133.00 | 27 | |
SU6656 inhibits Src family kinases, which are involved in signaling pathways related to cell growth and motility. Inhibition of Src kinases can impact downstream events, potentially influencing OCR1-related cellular processes. SU6656 may act as an indirect activator by disrupting Src kinase-mediated signaling cascades associated with pathways linked to OCR1 functions. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $184.00 $741.00 $1076.00 $3417.00 $5304.00 | 23 | |
A769662 is an AMP-activated protein kinase (AMPK) activator. Activation of AMPK can influence cellular energy metabolism and downstream signaling pathways, potentially impacting OCR1-related processes. A769662 may act as an indirect activator by promoting AMPK-mediated activation of signaling cascades associated with OCR1 functions. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD 98059 inhibits MEK1, a kinase in the MAPK/ERK pathway. Inhibition of MEK1 can impact downstream signaling cascades, potentially influencing OCR1-related cellular processes. PD 98059 may act as an indirect activator by disrupting MEK1-mediated events that intersect with pathways associated with OCR1 functions. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 inhibits PI3-kinases, affecting the PI3K/Akt pathway. Inhibition of PI3-kinases can influence downstream signaling events, potentially modulating OCR1-related cellular processes. LY294002 may act as an indirect activator by disrupting PI3K/Akt-mediated events that intersect with pathways associated with OCR1 functions. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB 203580 is a selective inhibitor of p38 MAPK. Inhibition of p38 MAPK can impact downstream signaling cascades, potentially influencing OCR1-related cellular processes. SB203580 may act as an indirect activator by preventing p38 MAPK-mediated signaling events that intersect with pathways associated with OCR1 functions. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
BAY 11-7082 inhibits NF-κB activation, a transcription factor involved in various cellular processes. Inhibition of NF-κB can influence gene expression, potentially modulating OCR1-related pathways. BAY 11-7082 may act as an indirect activator by preventing NF-κB-mediated events that intersect with pathways associated with OCR1 functions. | ||||||