NUDT13 Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sulindac | 38194-50-2 | sc-202823 sc-202823A sc-202823B | 1 g 5 g 10 g | $32.00 $86.00 $150.00 | 3 | |
Sulindac sulfide inhibits the Wnt signaling pathway by targeting the Dishevelled protein. Since NUDT13 is potentially associated with the regulation of gene expression, its activity could be diminished as a downstream effect of Wnt pathway inhibition. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major component of green tea, has been shown to interfere with the NF-κB pathway, which is involved in the expression of various genes, including potentially those regulated by NUDT13. By inhibiting NF-κB, EGCG may indirectly decrease NUDT13's functional activity. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $36.00 $117.00 $525.00 | 26 | |
XAV-939 is a tankyrase inhibitor that stabilizes Axin by preventing its poly(ADP-ribosyl)ation, leading to the downregulation of Wnt signaling. Given that NUDT13 may play a role in gene regulation downstream of Wnt, XAV-939 might lead to reduced NUDT13 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a MEK inhibitor that blocks the MAPK/ERK pathway, a key signaling route for cell proliferation and differentiation. NUDT13, if implicated in these processes, could be affected by the reduced activation of this pathway. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that could lead to decreased AKT phosphorylation, thereby affecting the cell survival pathways that might involve NUDT13. As a result, NUDT13's role in these pathways could be indirectly inhibited. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor that can disrupt the mTOR signaling pathway, which is crucial for cell growth and proliferation. If NUDT13 is involved in such pathways, its activity would be reduced as a consequence of mTOR inhibition. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a ROCK inhibitor, and by inhibiting Rho-associated kinases, it can modulate cytoskeletal dynamics. NUDT13, should it be linked to these processes, might have reduced activity due to alterations in cytoskeletal regulation. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Bortezomib is a proteasome inhibitor that can lead to the accumulation of misfolded proteins, potentially affecting protein turnover and functions related to NUDT13. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
Cyclopamine inhibits the Hedgehog signaling pathway by binding to Smoothened. If NUDT13 is implicated in gene expression mediated by Hedgehog signaling, its activity could be dampened by cyclopamine. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $96.00 $355.00 | 69 | |
Dorsomorphin is an inhibitor of BMP signaling by targeting the ALK2, ALK3, and ALK6 receptors. By interfering with this pathway, it could indirectly affect the functional activity of NUDT13 if it is involved in BMP-mediated processes. | ||||||