Date published: 2025-10-25

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Neuro D2 Inhibitors

Neuro D2 inhibitors represent a class of chemical compounds designed to target and modulate the activity of the protein Neuro D2, also known as Neurogenic Differentiation Factor 2. Neuro D2 is a transcription factor that belongs to the basic helix-loop-helix (bHLH) family of transcription factors, which are key regulators of gene expression in various developmental and cellular processes. Neuro D2, in particular, plays a pivotal role in neuronal differentiation and the development of the nervous system. It is involved in the transcriptional control of genes related to neurogenesis and neuronal differentiation, making it an essential factor in the formation and maturation of neurons.

The mechanisms by which Neuro D2 inhibitors function can vary based on their chemical structures and binding properties. Some inhibitors may directly interact with Neuro D2, disrupting its DNA-binding capacity or its ability to form transcriptional complexes with other regulatory proteins. Others may modulate the stability or subcellular localization of Neuro D2, thereby influencing its transcriptional activity. By inhibiting Neuro D2, these compounds have the potential to alter the expression patterns of genes involved in neuronal differentiation and development, ultimately impacting neurogenesis and the formation of the nervous system. Ongoing research in this field aims to uncover the precise mechanisms and downstream effects of Neuro D2 inhibition, contributing to our understanding of its role in neurobiology and developmental processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium chloride is known to influence several signaling pathways related to neurogenesis and neural function, potentially impacting Neuro D2 activity.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Valproic acid is a histone deacetylase inhibitor that can affect gene expression, potentially altering the activity of transcription factors like Neuro D2.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

As another histone deacetylase inhibitor, trichostatin A affects chromatin structure and gene expression, potentially influencing Neuro D2.

Wnt Agonist

853220-52-7sc-222416
sc-222416A
5 mg
25 mg
$154.00
$597.00
23
(2)

This Wnt pathway agonist could influence neural development and differentiation, indirectly affecting Neuro D2 activity.

DAPT

208255-80-5sc-201315
sc-201315A
sc-201315B
sc-201315C
5 mg
25 mg
100 mg
1 g
$99.00
$335.00
$836.00
$2099.00
47
(3)

DAPT is a gamma-secretase inhibitor affecting Notch signaling, which can influence neurogenesis and potentially Neuro D2 activity.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

As an inhibitor of MEK, PD98059 modulates the MAPK/ERK pathway, which is involved in various cellular processes including those associated with Neuro D2.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

This inhibitor of PI3K could affect signaling pathways related to cell survival and neurogenesis, indirectly influencing Neuro D2.

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$80.00
$212.00
$408.00
48
(1)

SB431542 is an inhibitor of the TGF-beta receptor, affecting pathways that could intersect with Neuro D2's role in neurogenesis.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

As an mTOR inhibitor, rapamycin can affect cellular processes like autophagy and protein synthesis, potentially impacting Neuro D2.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

This ROCK inhibitor affects cytoskeletal dynamics, which could indirectly influence the environment in which Neuro D2 functions.