NDUFS3 Activators
NDUFS3 Activators are a diverse group of chemical compounds that indirectly enhance the functional activity of NDUFS3, a crucial component of Complex I in the mitochondrial electron transport chain. These activators work through various mechanisms to promote mitochondrial health, thereby supporting the critical role of NDUFS3 in electron transport and ATP synthesis. Coenzyme Q10, by facilitating electron transfer within Complex I, directly contributes to the optimization of NDUFS3's function in ATP production. Resveratrol, a natural polyphenol, and Sirtuin activators, such as SRT1720, improve mitochondrial biogenesis and function, which in turn, indirectly enhances NDUFS3's efficiency in oxidative phosphorylation. Metformin, known for activating AMPK, and Nicotinamide riboside, an NAD+ precursor, both contribute to mitochondrial health, consequently supporting NDUFS3's function in electron transfer.
Additionally, compounds like Bezafibrate and PGC-1α activators, including Pioglitazone hydrochloride, stimulate mitochondrial biogenesis and respiration, indirectly augmenting NDUFS3 activity within the respiratory chain. Alpha-lipoic acid, due to its antioxidant properties, aids in maintaining mitochondrial integrity, thus supporting NDUFS3's role in the electron transport process. Methylene blue, acting as an electron carrier, specifically enhances electron transport efficiency in Complex I, where NDUFS3 is integral. Similarly, Acetyl-L-carnitine chloride, involved in fatty acid metabolism, indirectly promotes NDUFS3 activity by improving mitochondrial energy production. DL-Sulforaphane, an Nrf2 activator, and Curcumin, with its antioxidant effects, also contribute to the enhancement of mitochondrial function and protection. This collective enhancement of mitochondrial efficiency and protection plays a pivotal role in optimizing NDUFS3's function within the electron transport chain, underscoring its importance in energy production and cellular respiration.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Coenzyme Q10, a key component in the mitochondrial electron transport chain, indirectly enhances NDUFS3 activity by facilitating electron transfer within Complex I. This increased electron flow enhances NDUFS3 function in electron transport and ATP synthesis. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenol, indirectly activates NDUFS3 by promoting mitochondrial biogenesis and function. This upregulation supports NDUFS3's role in Complex I of the electron transport chain, enhancing oxidative phosphorylation. | ||||||
SRT1720 | 1001645-58-4 | sc-364624 sc-364624A | 5 mg 10 mg | $193.00 $357.00 | 13 | |
Sirtuin activators (such as SRT1720) enhance NDUFS3 activity indirectly by stimulating sirtuins, which are known to improve mitochondrial function. This improvement positively influences NDUFS3's role in the electron transport chain. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
Nicotinamide riboside, a precursor of NAD+, indirectly activates NDUFS3 by increasing NAD+ levels, thereby supporting mitochondrial function. Enhanced NAD+ levels positively affect NDUFS3's role in electron transport within Complex I. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
Bezafibrate, a PPAR agonist, indirectly enhances NDUFS3 activity by stimulating mitochondrial biogenesis and fatty acid oxidation. This leads to improved function of Complex I, where NDUFS3 is a crucial component. | ||||||
Pioglitazone hydrochloride | 112529-15-4 | sc-204848 sc-204848A | 100 mg 500 mg | $62.00 $209.00 | 19 | |
PGC-1α activators (such as Pioglitazone) indirectly enhance NDUFS3 activity by stimulating mitochondrial biogenesis and respiration, thus supporting NDUFS3's function in mitochondrial Complex I. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Alpha-lipoic acid, an antioxidant, indirectly enhances NDUFS3 activity by improving overall mitochondrial function and reducing oxidative stress. This supports NDUFS3’s role in the electron transport chain. | ||||||
Methylene blue | 61-73-4 | sc-215381B sc-215381 sc-215381A | 25 g 100 g 500 g | $42.00 $102.00 $322.00 | 3 | |
Methylene blue, an electron carrier, indirectly activates NDUFS3 by enhancing electron transport in the mitochondrial respiratory chain, particularly in Complex I where NDUFS3 is vital. | ||||||
Acetyl-L-carnitine chloride | 5080-50-2 | sc-210747 | 1 g | $52.00 | ||
Acetyl-L-carnitine chloride, involved in fatty acid metabolism, indirectly activates NDUFS3 by improving mitochondrial function and energy production, thereby enhancing NDUFS3’s role in the electron transport chain. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
DL-Sulforaphane, an Nrf2 activator, indirectly enhances NDUFS3 activity by promoting mitochondrial protection and function, thereby supporting NDUFS3's role in Complex I of the electron transport chain. | ||||||