Acetyl-L-carnitine chloride CAS: 5080-50-2
MF: C9H18NClO4
MW: 239.7
A cholinergic agonist that stimulates neuronal response to serotonin and acetylcholine.

Acetyl-L-carnitine chloride (CAS 5080-50-2)

Acetyl-L-carnitine chloride | CAS 5080-50-2 is rated 5.0 out of 5 by 1.
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Alternate Names: R-(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride
Application: Acetyl-L-carnitine chloride is a cholinergic agonist that stimulates neuronal response to serotonin and acetylcholine
CAS Number: 5080-50-2
Purity: ≥99%
Molecular Weight: 239.7
Molecular Formula: C9H18NClO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.


References

Effect of l-carnitine chloride and its acetyl derivative on the electrophysiological derangement induced by palmityl-l-carnitine in isolated canine ventricular muscle: K. Matsui, et al.; Jpn. J. Pharmacol. 39, 263 (1985)

Physical State :
Solid
Solubility :
Soluble in water (100 mg/ml), alcohol, and ethanol (10%). Insoluble in ether.
Storage :
Store at 4° C
Melting Point :
194° C (dec.)
Optical Activity :
α20/D -28°, c = 2 in water; α20/D°
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
2733928
Merck Index :
14: 84
MDL Number :
MFCD00082230
Beilstein Registry :
4340103
SMILES :
[Cl-].CC(=O)O[[email protected]](CC(O)=O)C[N+](C)(C)C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Galeotti N; et al Galeotti N; et al. (PubMed ID: 15223307) determined that Acetyl-L-carnitine chloride induced analgesia in mice must activate the PLC-IP(3) pathway to have an effect. -SCBT Publication Review
Date published: 2015-07-02
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