Date published: 2026-4-28

1-800-457-3801

SCBT Portrait Logo
Seach Input

NCDN Inhibitors

NCDN inhibitors belong to a fascinating chemical class that has garnered significant attention and scientific interest in recent years. These inhibitors are compounds specifically designed and synthesized to target a protein called NCDN, which plays a vital role in various cellular processes. The acronym NCDN stands for neuronal calcium-binding protein and dendritic spine maturation factor, indicating its involvement in neuronal development and synaptic plasticity. NCDN inhibitors possess a unique molecular structure that allows them to interact with the active site of the NCDN protein. By binding to this active site, the inhibitors effectively hinder the normal function of NCDN and disrupt the associated signaling pathways and molecular cascades in which NCDN is involved. This interference at the molecular level offers researchers a valuable tool for investigating the intricate mechanisms underlying cellular processes regulated by NCDN.

The discovery and characterization of NCDN inhibitors have provided scientists with a means to explore the physiological consequences of inhibiting NCDN activity. Through comprehensive studies and meticulous experiments, researchers aim to unravel the precise molecular and physiological effects induced by NCDN inhibition. These investigations help elucidate the role of NCDN in various cellular contexts and shed light on its significance in neuronal development, synaptic plasticity, and other cellular processes. The chemical class of NCDN inhibitors represents a remarkable advancement in our understanding of cellular biology. Their specific and targeted action on NCDN provides scientists with an opportunity to explore the intricate interactions between this protein and other molecular components within cells. By deciphering the underlying molecular mechanisms associated with NCDN inhibition, researchers can gain valuable insights into fundamental cellular processes and pathways. Moreover, the availability of NCDN inhibitors opens up new avenues for experimental studies in scientific research. Researchers can utilize these inhibitors to manipulate NCDN activity and observe the resulting effects on cellular function and behavior. This knowledge can contribute to a deeper understanding of the fundamental principles governing cellular processes and pave the way for further discoveries in the field of molecular biology.

SEE ALSO...

Items 1 to 10 of 14 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Donepezil

120014-06-4sc-279006
10 mg
$74.00
3
(1)

Acetylcholinesterase inhibitor used in Alzheimer's disease, enhances neurotransmission by inhibiting the breakdown of acetylcholine.

MLN 4924

905579-51-3sc-484814
1 mg
$286.00
1
(0)

MLN4924 is a potent and selective NAE inhibitor that has demonstrated anticancer activity. It blocks the activation of NEDD8 and disrupts the function of Cullin-RING E3 ligases, leading to the stabilization of their substrate proteins and inducing cell cycle arrest and apoptosis in cancer cells.

Memantine hydrochloride

41100-52-1sc-203628
50 mg
$69.00
4
(2)

NMDA receptor antagonist used in Alzheimer's disease, modulates glutamate signaling to reduce excitotoxicity.

MLN7243

1450833-55-2sc-507338
5 mg
$340.00
(0)

TAK-243 is a second-generation NAE inhibitor developed as an improved version of MLN492It exhibits enhanced potency and selectivity, with the potential to overcome certain limitations observed with MLN4924.

(S)-Rivastigmine

123441-03-2sc-472567
500 mg
$300.00
(0)

Acetylcholinesterase inhibitor for Alzheimer's, improves cholinergic transmission.

Galanthamine

357-70-0sc-218556
10 mg
$320.00
(0)

Acetylcholinesterase inhibitor, also modulates nicotinic receptors to enhance cognitive function in Alzheimer's.

GSK 923295

1088965-37-0sc-490136
5 mg
$290.00
(0)

GSK923295 is a selective NAE inhibitor that has demonstrated antitumor activity in various cancer models. It inhibits the NEDD8-activating enzyme, leading to the accumulation of Cullin-RING E3 ligase substrates and inducing cell cycle arrest and apoptosis.

Levodopa

59-92-7sc-205372
sc-205372A
5 g
25 g
$54.00
$171.00
9
(1)

Precursor to dopamine used in Parkinson's disease, replenishes dopamine levels in the brain.

S(−)-Carbidopa

28860-95-9sc-200749
sc-200749A
25 mg
100 mg
$96.00
$275.00
5
(0)

Enhances L-DOPA's effectiveness by blocking its conversion to dopamine outside the brain.

Riluzole

1744-22-5sc-201081
sc-201081A
sc-201081B
sc-201081C
20 mg
100 mg
1 g
25 g
$20.00
$193.00
$213.00
$317.00
1
(1)

Modulates glutamate signaling and may slow down disease progression in ALS (Amyotrophic lateral sclerosis).