NAT-13 activators refer to a class of chemicals that specifically enhance the activity of NAT-13, an enzyme involved in essential cellular processes. The primary function of these activators is to increase the enzymatic activity of NAT-13, thereby influencing the biochemical pathways it regulates. This enhancement can lead to modifications in the metabolic processes associated with NAT-13, including those related to the synthesis and breakdown of critical cellular components. The mechanism by which NAT-13 activators exert their effects can vary, encompassing direct interaction with the enzyme to promote its catalytic efficiency, altering its expression levels within the cell, or modifying the enzyme's accessibility to its substrates. These activators are carefully studied through biochemical assays that assess their impact on enzyme activity, including kinetic analyses to determine how they affect the rate of reaction catalyzed by NAT-13.
Research into NAT-13 activators incorporates a variety of scientific techniques aimed at understanding their mechanism of action at a molecular level. Molecular biology methods, such as gene expression analysis and protein quantification, are utilized to observe changes in NAT-13 levels following the application of these activators. Additionally, structural biology approaches, including X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy, may be employed to elucidate the binding sites of activators on NAT-13 and to visualize conformational changes in the enzyme that enhance its activity. The goal of this research is not only to map out the interaction between NAT-13 and its activators but also to comprehend how these interactions affect the enzyme's role in cellular processes. By advancing our knowledge of NAT-13 activators, scientists can gain deeper insights into the biological functions mediated by NAT-13, shedding light on the complex networks of metabolic and signaling pathways within the cell. This understanding contributes to the broader field of biochemistry and cellular biology, offering a detailed view of how specific enzyme activators can modulate cellular functions through precise molecular mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane may upregulate detoxification enzymes as it activates Nrf2, a transcription factor that induces the expression of various cytoprotective genes. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has been shown to modulate various signaling pathways and may upregulate genes involved in metabolism and detoxification processes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a polyphenolic compound that can influence the expression of genes associated with oxidative stress and may affect detoxifying enzymes. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid, has antioxidant properties and might induce the expression of enzymes involved in detoxification and metabolic processes. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $38.00 $60.00 $143.00 $306.00 $1012.00 | 5 | |
Found in cruciferous vegetables, it can modulate xenobiotic metabolism and potentially influence N-acetyltransferase expression. | ||||||
Oltipraz | 64224-21-1 | sc-205777 sc-205777A | 500 mg 1 g | $286.00 $622.00 | ||
Oltipraz has been shown to modulate detoxification pathways and could potentially induce the expression of enzymes like N-acetyltransferases. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Rifampicin can upregulate metabolic enzymes as it is a potent inducer of cytochrome P450 enzymes through pregnane X receptor (PXR) activation. | ||||||
Diallyl sulfide | 592-88-1 | sc-204718 sc-204718A | 25 g 100 g | $41.00 $104.00 | 3 | |
Found in garlic, it may induce phase II detoxification enzymes, which could include N-acetyltransferases. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Ellagic acid has been reported to modulate phase II detoxifying enzymes, suggesting a possible effect on N-acetyltransferase expression. | ||||||
t-Butylhydroquinone | 1948-33-0 | sc-202825 | 10 g | $66.00 | 4 | |
tBHQ can induce antioxidant response element-mediated expression of detoxification enzymes, potentially including N-acetyltransferases. | ||||||