Date published: 2026-5-16

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Myosin-neonatal Inhibitors

Myosin-neonatal inhibitors are a class of chemical compounds specifically designed to target and inhibit the function of the neonatal isoform of myosin, a motor protein that plays a crucial role in muscle contraction and various cellular movements. Myosin is a superfamily of motor proteins that interact with actin filaments to generate force and movement within cells. The neonatal isoform of myosin, often expressed during early developmental stages, is particularly important in the formation and function of muscle tissue in neonates. This isoform is structurally distinct from the adult forms of myosin, which allows it to fulfill specialized roles during the early stages of muscle development. By inhibiting the neonatal isoform of myosin, researchers can study its specific contributions to muscle formation, differentiation, and function during development.

In research settings, myosin-neonatal inhibitors are valuable tools for exploring the role of this specific myosin isoform in the development and function of neonatal muscle tissue. By blocking the activity of neonatal myosin, scientists can investigate how the inhibition affects muscle fiber formation, contractile properties, and the overall development of muscle tissue during the neonatal period. These inhibitors allow researchers to dissect the differences between neonatal and adult myosin isoforms in terms of their structural and functional properties, providing insights into the specialized roles that neonatal myosin plays in muscle physiology. Additionally, myosin-neonatal inhibitors help in understanding the regulatory mechanisms that control the expression and activity of different myosin isoforms during development, contributing to a broader understanding of muscle biology and the molecular processes that drive muscle differentiation and maturation. Through these studies, the use of myosin-neonatal inhibitors enhances our knowledge of the critical role that myosin isoforms play in muscle development and the specific functions of neonatal myosin in early life stages.

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Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(±)-Blebbistatin

674289-55-5sc-203532B
sc-203532
sc-203532A
sc-203532C
sc-203532D
5 mg
10 mg
25 mg
50 mg
100 mg
$183.00
$313.00
$464.00
$942.00
$1723.00
7
(1)

Selective inhibitor of myosin II, can inhibit MYH8 through its effects on myosin.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

Inhibits Rho-associated kinase, thus reducing muscle contractility and potentially inhibiting MYH8.

ML-9

105637-50-1sc-200519
sc-200519A
sc-200519B
sc-200519C
10 mg
50 mg
100 mg
250 mg
$112.00
$449.00
$673.00
$1224.00
2
(1)

Inhibits myosin light chain kinase, which can in turn reduce the activity of MYH8.

Wiskostatin

253449-04-6sc-204399
sc-204399A
sc-204399B
sc-204399C
1 mg
5 mg
25 mg
50 mg
$49.00
$124.00
$441.00
$828.00
4
(1)

Inhibits the N-WASP-Arp2/3 pathway, potentially reducing the activity of MYH8 in cellular processes.

SB 202190

152121-30-7sc-202334
sc-202334A
sc-202334B
1 mg
5 mg
25 mg
$31.00
$128.00
$454.00
45
(1)

p38 MAPK inhibitor, can influence MYH8 by inhibiting muscle differentiation.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor, can indirectly inhibit the activity of MYH8 in stress response.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Inhibits MEK, which can affect pathways in which MYH8 is involved.

Gö 6983

133053-19-7sc-203432
sc-203432A
sc-203432B
1 mg
5 mg
10 mg
$105.00
$299.00
$474.00
15
(1)

PKC inhibitor, can affect MYH8 function via PKC-related pathways.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

PI3K inhibitor that can indirectly affect MYH8 functionality.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Another PI3K inhibitor, can affect MYH8 activity by inhibiting signaling pathways.