MYBPC3 Activators
MYBPC3 Activators belong to a class of chemical compounds that are involved in the modulation of the protein Myosin-binding protein C cardiac-type (MYBPC3). MYBPC3 is a critical regulatory protein predominantly expressed in cardiac muscle. It plays a crucial role in the regulation of muscle contraction, particularly in the sarcomere structure of cardiac muscle cells. MYBPC3 interacts with myosin and actin filaments, serving as a scaffold and contributing to the organization and stability of the sarcomere. Additionally, MYBPC3 plays a role in the fine-tuning of muscle contraction by regulating the interaction between myosin and actin, which is essential for proper cardiac function. MYBPC3 Activators are small molecules designed to interact with MYBPC3, modulating its activity and influence over cardiac muscle contraction.
The mechanism of action of MYBPC3 Activators typically involves binding to specific regions of the MYBPC3 protein, inducing conformational changes that may affect its interactions with myosin, actin, or other regulatory proteins within the sarcomere. By modulating MYBPC3 activity, these activators impact the dynamics of muscle contraction in cardiac muscle cells. Research into MYBPC3 Activators provides insights into the complex regulatory mechanisms governing cardiac muscle function and sarcomere organization. Understanding how these activators interact with MYBPC3 contributes to our knowledge of the intricate balance between contraction and relaxation in cardiac muscle cells.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
A non-selective beta-adrenergic agonist that enhances cardiac contractility, potentially increasing MYBPC3 function. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels, which can indirectly enhance cardiac muscle contraction and possibly MYBPC3 activity. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
A phosphodiesterase inhibitor, raising cAMP levels and potentially influencing MYBPC3 activity by enhancing myocardial contractility. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
A potent stimulator of cardiac output, potentially enhancing MYBPC3 function through increased cardiac muscle contraction. | ||||||
12β-Hydroxydigitoxin | 20830-75-5 | sc-213604 sc-213604A | 1 g 5 g | $143.00 $694.00 | ||
Increases intracellular calcium in cardiac cells, potentially enhancing MYBPC3 function by improving contractile force. | ||||||
Dobutamine | 34368-04-2 | sc-507555 | 100 mg | $295.00 | ||
A beta-1 adrenergic agonist, increases myocardial contractility, possibly affecting MYBPC3 activity. | ||||||
Milrinone | 78415-72-2 | sc-201193 sc-201193A | 10 mg 50 mg | $165.00 $697.00 | 7 | |
A phosphodiesterase-3 inhibitor, increases cAMP and enhances cardiac contractility, potentially influencing MYBPC3. | ||||||
Levosimendan | 141505-33-1 | sc-204792 sc-204792A | 100 mg 250 mg | $104.00 $228.00 | ||
Increases calcium sensitivity of the heart, potentially enhancing MYBPC3 activity. | ||||||
Amrinone | 60719-84-8 | sc-207288 | 1 g | $193.00 | ||
A phosphodiesterase inhibitor, increases cAMP in cardiac cells, potentially affecting MYBPC3 activity. | ||||||
L-Noradrenaline | 51-41-2 | sc-357366 sc-357366A | 1 g 5 g | $326.00 $485.00 | 3 | |
A neurotransmitter that can enhance cardiac contractility, indirectly influencing MYBPC3 function. | ||||||