MXRA7 Inhibitors
MXRA7 inhibitor Disulfiram, traditionally used in the management of chronic alcohol dependence, has been shown to inhibit MMP activity and consequently could influence MXRA7 by altering ECM dynamics. Selective inhibitors like NNGH, SB-3CT, and PD166793 specifically target certain MMPs, offering a more focused approach to controlling ECM remodeling in relation to MXRA7 function.
Other compounds such as TAPI-0 act on the ADAM family of enzymes, which also play roles in ECM modulation. By inhibiting these enzymes, TAPI-0 can affect the cleavage of membrane-bound precursors into active proteins that participate in matrix remodeling, indirectly affecting MXRA7 activity. WAY-170523 and NSC 405020 represent a different strategy, targeting MMP-13 and integrin-linked kinase (ILK), respectively. MMP-13 is a collagenase implicated in the degradation of collagen, a major ECM component, while ILK is key in cell-ECM interactions. By disturbing these targets, these inhibitors can impact the remodeling processes and signaling cascades that potentially involve MXRA7.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Marimastat | 154039-60-8 | sc-202223 sc-202223A sc-202223B sc-202223C sc-202223E | 5 mg 10 mg 25 mg 50 mg 400 mg | $168.00 $218.00 $404.00 $629.00 $4900.00 | 19 | |
A broad-spectrum matrix metalloproteinase (MMP) inhibitor; can affect ECM remodeling processes in which MXRA7 may be involved. | ||||||
GM 6001 | 142880-36-2 | sc-203979 sc-203979A | 1 mg 5 mg | $77.00 $270.00 | 55 | |
An MMP inhibitor that can prevent ECM degradation, potentially impacting the activity of matrix-remodeling proteins like MXRA7. | ||||||
Doxycycline Hyclate | 24390-14-5 | sc-204734B sc-204734 sc-204734A sc-204734C | 100 mg 1 g 5 g 25 g | $27.00 $50.00 $105.00 $194.00 | 25 | |
An antibiotic with MMP inhibitory activity; can alter ECM dynamics and possibly influence MXRA7-associated pathways. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
A compound that can inhibit MMPs and thus may affect ECM remodeling and indirectly influence MXRA7 function. | ||||||
SB-3CT | 292605-14-2 | sc-205847 sc-205847A | 1 mg 5 mg | $102.00 $388.00 | 15 | |
A selective inhibitor of MMP-2 and MMP-9, can impact matrix remodeling, possibly affecting MXRA7-related processes. | ||||||
PD166793 | 199850-67-4 | sc-202709 | 5 mg | $150.00 | 6 | |
A synthetic MMP inhibitor that can alter ECM composition and may thereby exert an indirect effect on MXRA7 function. | ||||||
Batimastat | 130370-60-4 | sc-203833 sc-203833A | 1 mg 10 mg | $179.00 $377.00 | 24 | |
A synthetic inhibitor of MMPs that can impede ECM degradation, potentially modifying MXRA7 function. | ||||||
WAY 170523 | 307002-73-9 | sc-361402 sc-361402A | 1 mg 10 mg | $275.00 $595.00 | 1 | |
An inhibitor of MMP-13, which may affect ECM turnover and thus influence processes related to MXRA7. | ||||||
NSC 405020 | 7497-07-6 | sc-477738 | 10 mg | $105.00 | ||
A small molecule that disrupts integrin-linked kinase (ILK) function, which is involved in cell-ECM adhesion; this may affect MXRA7 function indirectly. | ||||||