MRFAP1 activators encompass a class of chemical compounds that can potentially modulate its activity indirectly through mechanisms such as epigenetic modifications and transcriptional regulation. MRFAP1, a relatively understudied protein, plays a role in gene transcription and likely operates within larger transcriptional complexes. The chemicals identified within this class can indirectly influence MRFAP1 by impacting these transcriptional and epigenetic processes. For instance, trichostatin A, a histone deacetylase inhibitor, can alter chromatin structure and gene expression. It might indirectly affect MRFAP1 by modulating the acetylation status of histones, thereby influencing the transcriptional processes governed by MRFAP1-associated genes.
Additionally, compounds like 5-azacytidine, a DNA methyltransferase inhibitor, possess the capability to demethylate gene promoters. These changes in DNA methylation patterns have the potential to indirectly impact MRFAP1 by altering the epigenetic landscape of genes under its transcriptional control. Curcumin and resveratrol, known for modulating various transcription factors and gene expression, respectively, hold the potential to influence MRFAP1 activity through their effects on transcriptional regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor that can alter chromatin structure and gene expression, potentially impacting MRFAP1 indirectly. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor that can demethylate gene promoters, potentially influencing MRFAP1 through epigenetic changes. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates various transcription factors, potentially affecting MRFAP1 indirectly through its influence on transcriptional processes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A polyphenolic compound that can activate sirtuins and influence gene expression, potentially impacting MRFAP1 indirectly via transcriptional regulation. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Anticonvulsant and mood-stabilizing drug that inhibits histone deacetylases, potentially affecting chromatin structure and gene expression, and indirectly influencing MRFAP1. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
Widely used solvent in cell culture studies that may affect cell signaling pathways, potentially influencing MRFAP1 indirectly. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
A form of vitamin B3 that can affect cellular metabolism and gene expression, potentially influencing MRFAP1 indirectly through its impact on cellular processes. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
HDAC inhibitor used in cancer therapy, potentially impacting MRFAP1 indirectly by modulating chromatin structure and gene expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
HDAC inhibitor that influences histone acetylation and gene expression, potentially affecting MRFAP1 indirectly. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Chemotherapy drug that can influence DNA topoisomerases and gene expression, potentially impacting MRFAP1 indirectly. | ||||||