Mlx Activators
The class of Mlx activators is characterized by a diverse range of chemical compounds that influence the cellular and molecular context in which Mlx operates. These activators do not directly bind to or interact with Mlx; instead, they modulate various signaling pathways and transcriptional regulation processes, creating an environment conducive to altering Mlx activity. For instance, compounds like Retinoic Acid and 5-Azacytidine work at the genomic level, influencing gene expression patterns that could affect Mlx's regulatory roles. Similarly, HDAC inhibitors such as Trichostatin A and Sodium Butyrate alter chromatin structure, which can have downstream effects on the transcriptional activities involving Mlx.
On the other hand, compounds like Lithium Chloride, Rapamycin, and Forskolin act through specific signaling pathways. Lithium Chloride's effect on the Wnt pathway, Rapamycin's inhibition of mTOR signaling, and Forskolin's elevation of cAMP levels demonstrate how alterations in these pathways can indirectly influence Mlx's activity in the cell. Moreover, the PI3K and MAPK pathways, targeted by compounds like LY294002, PD98059, SB203580, and U0126, are integral to various cellular processes, including proliferation, differentiation, and stress responses. The modulation of these pathways can indirectly affect Mlx, highlighting the interconnected nature of cellular signaling and transcriptional regulation.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influences gene expression by acting on retinoic acid receptors, which can alter the transcriptional activity involving Mlx by modulating its partnering proteins. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor, TSA alters chromatin structure, potentially affecting the transcriptional regulation of genes where Mlx is involved. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can lead to the demethylation of genes, potentially affecting Mlx activity through altered gene expression patterns. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences the Wnt signaling pathway. Though not directly linked to Mlx, altered Wnt signaling can modify the cellular context where Mlx functions. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR signaling, potentially influencing the cellular environment and transcriptional regulation in a manner that indirectly affects Mlx activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylyl cyclase, increasing cAMP levels, which can modulate cellular signaling pathways potentially affecting Mlx-regulated gene expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
An HDAC inhibitor like TSA, it affects chromatin structure and gene expression, potentially influencing Mlx activity through transcriptional regulation changes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, can indirectly affect Mlx activity through alterations in the PI3K/Akt signaling pathway, impacting cellular processes and gene expression. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, potentially influencing Mlx activity by altering signaling in cellular stress responses and inflammatory processes. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Another MEK inhibitor, it can indirectly affect Mlx activity through changes in the MAPK pathway, which is involved in various cellular processes. | ||||||