Date published: 2026-4-1

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mKIAA1530 Activators

mKIAA1530 Activators are a diverse group of chemical compounds that indirectly enhance the functional activity of mKIAA1530 through various cellular pathways, particularly focusing on DNA repair mechanisms and responses to UV damage. Curcumin and Sulforaphane, by modulating DNA repair pathways, indirectly augment mKIAA1530's involvement in transcription-coupled nucleotide-excision repair (TC-NER). These compounds, through their respective roles in enhancing DNA repair mechanisms, indirectly facilitate the function of mKIAA1530, especially in response to UV-induced DNA damage. Resveratrol, through its influence on sirtuin pathways, particularly SIRT1, and Ellagic Acid, by modulating DNA repair processes, support mKIAA1530's activity in the nucleoplasm and on chromosomes. Similarly, Caffeine, by inhibiting ATM and ATR kinases, and KU-55933, as an ATM kinase inhibitor, indirectly impact TC-NER pathways where mKIAA1530 is pivotal. These compounds, by influencing key kinases involved in DNA damage response, indirectly enhance mKIAA1530's role in DNA repair.

Additionally, compounds like Olaparib, a PARP inhibitor, and Nordihydroguaiaretic Acid, which affects oxidative stress response pathways, further influence the DNA repair mechanisms in which mKIAA1530 is involved. Olaparib, by inhibiting PARP, an enzyme crucial in DNA repair, indirectly supports mKIAA1530's function in TC-NER. Quercetin and Epigallocatechin Gallate, by influencing the cellular response to oxidative stress, play a role in enhancing mKIAA1530's function in UV-induced DNA damage repair. Genistein's modulation of tyrosine kinase-dependent signaling pathways also indirectly supports mKIAA1530's involvement in DNA repair, providing an additional layer of regulation. Lastly, Urolithin A, by influencing mitophagy and the oxidative stress response, supports DNA repair mechanisms, including those involving mKIAA1530, particularly in response to UV and oxidative damage, thus contributing to the overall enhancement of mKIAA1530's activity. These compounds, through their targeted effects on different aspects of cellular signaling and stress response, collectively enhance the functional role of mKIAA1530 in crucial biological processes such as transcription-coupled nucleotide-excision repair, DNA damage response, and maintenance of genomic integrity. Their actions, although varied in mechanism, converge on the common goal of facilitating mKIAA1530's role in maintaining cellular health in the face of DNA damage, particularly damage caused by UV exposure. The synergy between these activators and mKIAA1530's functions exemplifies the intricate network of cellular responses to environmental stressors and the essential role of mKIAA1530 in navigating these responses to preserve genomic stability.

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Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin enhances DNA repair mechanisms, including transcription-coupled nucleotide-excision repair, which mKIAA1530 is involved in. By modulating pathways that respond to DNA damage, curcumin indirectly supports mKIAA1530's role in these processes.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol, by influencing sirtuin pathways, particularly SIRT1, indirectly affects DNA repair processes, including those mediated by mKIAA1530. Its role in chromatin remodeling aids the function of mKIAA1530 in the nucleoplasm and on chromosomes.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Caffeine, a known inhibitor of ATM and ATR kinases, indirectly affects DNA repair pathways. By modulating these kinases, caffeine can influence the transcription-coupled nucleotide-excision repair processes where mKIAA1530 is involved.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Sulforaphane enhances DNA repair mechanisms, including those involved in the response to UV. By activating Nrf2, it indirectly supports mKIAA1530's role in DNA repair, especially in response to oxidative stress and UV exposure.

Olaparib

763113-22-0sc-302017
sc-302017A
sc-302017B
250 mg
500 mg
1 g
$210.00
$305.00
$495.00
10
(1)

Olaparib, a PARP inhibitor, indirectly influences DNA repair pathways, including transcription-coupled nucleotide-excision repair, where mKIAA1530 functions. It affects DNA repair mechanisms by inhibiting PARP, an enzyme involved in DNA repair.

Ellagic Acid, Dihydrate

476-66-4sc-202598
sc-202598A
sc-202598B
sc-202598C
500 mg
5 g
25 g
100 g
$58.00
$95.00
$245.00
$727.00
8
(1)

Ellagic Acid has a role in modulating DNA repair mechanisms. By influencing the pathways that respond to DNA damage, it indirectly supports the functional activity of mKIAA1530 in transcription-coupled nucleotide-excision repair processes.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin influences pathways involved in the cellular response to oxidative stress, indirectly supporting mKIAA1530's function in DNA repair processes, especially in response to UV-induced DNA damage.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

Epigallocatechin Gallate affects cellular antioxidant responses and DNA repair mechanisms. By modulating these pathways, it indirectly supports the function of mKIAA1530 in transcription-coupled nucleotide-excision repair.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein, by modulating tyrosine kinase-dependent signaling pathways, indirectly influences DNA repair mechanisms. This modulation supports mKIAA1530's role in transcription-coupled nucleotide-excision repair.

ATM Kinase Inhibitor

587871-26-9sc-202963
2 mg
$110.00
28
(2)

KU-55933 is an ATM kinase inhibitor, affecting the DNA damage response. By modulating ATM kinase activity, it indirectly influences transcription-coupled nucleotide-excision repair, a process where mKIAA1530 is involved.