Date published: 2025-11-18

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MHC class II Antibodies

Santa Cruz Biotechnology offers a broad range of MHC class II Antibodies for research in immunology and cell biology. MHC class II Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MHC class II molecules play a crucial role in the immune system by presenting antigens to CD4+ T cells, which are essential for initiating and regulating immune responses. The proper functioning of MHC class II molecules is vital for the recognition of pathogens and the activation of adaptive immunity. Dysregulation of MHC class II expression is associated with various autoimmune diseases and can impact vaccine efficacy. Understanding MHC class II molecules helps advance knowledge in transplantation biology and cancer immunotherapy. Research using MHC class II molecules contributes to developing new therapeutic strategies for autoimmune disorders. Investigating MHC class II expression patterns provides insights into immune system development and function. Santa Cruz Biotechnology monoclonal antibodies for MHC class II enable researchers to advance scientific understanding of immune system regulation and disease mechanisms.

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MHC class II Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MHC class II Antibody (Y-Ae)

sc-32247mouse IgG2b λ(m)WB, IP, IF, IHC(P), FCMm
16
(4)

MHC class II Antibody (IBL-5/22)

sc-59322rat IgG1(m)WB, IP, IF, FCMm
22
(8)

MHC class II Antibody (ER-TR3)

sc-59318rat IgG2bFL (m)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
14
(2)

MHC class II Antibody (12F4)

sc-53896mouse IgG1 κ(h)IFh
3
(2)

MHC class II Antibody (ER-TR2)

sc-59317rat IgG2bFL (m)IF, FCM, ELISAm
1
(1)

MHC class II Antibody (11-5.2)

sc-53726mouse IgG2b κ(m)IP, IF, FCMm

new

(1)

MHC class II Antibody (15G4)

sc-53946mouse IgG1 κ(m)IP, IF, FCMm
4
(2)

MHC class II Antibody (TE12)

sc-73601mouse IgG1 κ(h)IFh
1
(1)

MHC class II CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HLA-DQB1 CRISPR/Cas9 KO Plasmid (m)

sc-420756mGene KnockoutGFP0
(0)

HLA-DQB1 Double Nickase Plasmid (m)

sc-420756-NICmGene KnockoutPuromycin0
(0)

HLA-DQB1 Double Nickase Plasmid (m2)

sc-420756-NIC-2mGene KnockoutPuromycin0
(0)

MHC class II CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HLA-DQB1 CRISPR Activation Plasmid (m)

sc-420756-ACTmGene ActivationPuro, Blast, Hygro0
(0)

HLA-DQB1 CRISPR Activation Plasmid (m2)

sc-420756-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

HLA-DQB1 Lentiviral Activation Particles (m)

sc-420756-LACmGene ActivationPuro, Blast, Hygro0
(0)

HLA-DQB1 Lentiviral Activation Particles (m2)

sc-420756-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

MHC class II siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MHC class II siRNA (m)

sc-72123mGene SilencingN/A
1
(0)

MHC class II shRNA Plasmid (m)

sc-72123-SHmGene SilencingPuromycin
1
(0)

MHC class II shRNA (m) Lentiviral Particles

sc-72123-VmGene SilencingPuromycin
1
(0)