MHC class I Antibodies

Santa Cruz Biotechnology offers a broad range of MHC class I monoclonal antibodies for advanced research in immunology and cell biology. MHC class I monoclonal antibodies are compatible with multiple experimental techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MHC class I molecules play a critical role in the immune response by presenting endogenous peptides to CD8+ T cells, thus enabling the detection and elimination of infected or malignant cells. Their proper functioning is essential for immune surveillance and the maintenance of self-tolerance. Understanding MHC class I molecules has significant implications for autoimmune diseases, cancer immunotherapy, and transplant rejection research. Ongoing studies continue to reveal new insights about MHC class I's role in cellular immunity and disease progression. Research focusing on MHC class I has led to breakthroughs in understanding immune system regulation and potential therapeutic approaches. The high specificity and reliability of Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of immune system function and disease mechanisms.