MHC class I Antibody (BRA23/9): sc-66205

MHC class I Antibody (BRA23/9) is a mouse monoclonal IgG2a antibody engineered to detect Major Histocompatibility Complex class I (MHC I) proteins, also known as Human Leukocyte Antigen (HLA) class I molecules, in human samples. Anti-MHC class I antibody (BRA23/9) targets an epitope derived from the REH cell line of human origin, ensuring precise and reliable binding across various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). MHC class I proteins are essential cell-surface receptors that present endogenous peptides, typically 8-10 amino acids in length, to cytotoxic T lymphocytes, thereby enabling the immune system to identify and eliminate infected or malignant cells. This critical function is fundamental for immune surveillance and the maintenance of cellular homeostasis. By accurately detecting MHC class I expression, anti-MHC class I antibody (BRA23/9) facilitates the study of antigen presentation, immune cell interactions, and related immune mechanisms with high specificity and minimal cross-reactivity, reducing background noise and enhancing experimental accuracy. Available in both conjugated and unconjugated forms, MHC class I monoclonal antibody (BRA23/9) offers versatility for diverse experimental setups, accommodating various detection systems and protocols. The high affinity and specificity of anti-MHC class I antibody (BRA23/9) make this reagent an invaluable tool for researchers in immunology, oncology, and other biomedical fields, contributing to a deeper understanding of immune responses and the development of targeted therapies.

The preferred MHC class I antibody is MHC class I Antibody (W6/32): sc-32235.