MHC class I Antibody (ER-MP42): sc-59200
- MHC class I Antibody (ER-MP42) is a rat monoclonal IgG2a provided at 200 µg/ml
- raised against macrophage precursor cells of mouse origin
- recommended for detection of MHC class I molecules on the surface of cells of the following haplotypes: H2-Fv, H2-Dd, H2k,q, s and, to a lesser extent, H2p,r,w7,w22 of mouse origin by IF and FCM; non cross-reactive with MHC class I molecules of other haplotypes
- See MHC class I (ER-HR52): sc-59199 for MHC class I antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MHC class I Antibody (ER-MP42). This work is in progress.
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MHC class I Antibody (ER-MP42) is a rat monoclonal IgG2a antibody designed to detect Major Histocompatibility Complex class I (MHC I) proteins, also known as H-2 class I molecules in mice, across various mouse haplotypes including H2-Fv, H2-Dd, H2k, q, s and, to a lesser extent, H2p, r, w7, w22. MHC class I monoclonal antibody (ER-MP42) specifically targets MHC class I proteins located on the cell surface, where these proteins play a crucial role in the immune system by presenting endogenous peptides to cytotoxic T lymphocytes, enabling immune surveillance and response. Structurally, MHC class I molecules are composed of a heavy α chain and a light β2-microglobulin chain, a configuration essential for stable binding and presentation of antigenic peptides within the peptide-binding groove. MHC class I (ER-MP42) antibody is optimized for use in immunofluorescence (IF) and flow cytometry (FCM) applications, allowing researchers to accurately detect and quantify MHC class I expression in various cellular environments. Available in both conjugated and unconjugated forms, MHC class I (ER-MP42) monoclonal antibody offers versatile options for diverse experimental designs, including studies on antigen presentation, immune cell interactions, and T cell-mediated responses. By enabling precise analysis of MHC class I distribution and function, MHC class I (ER-MP42) antibody serves as an invaluable tool for advancing immunological research and deepening our understanding of immune mechanisms and cellular communication.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MHC class I Antibody (ER-MP42) | sc-59200 | 200 µg/ml | $322.00 |