mGLuR-8 Inhibitors
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(RS)-CPPG | 183364-82-1 | sc-203448 sc-203448A | 5 mg 25 mg | $416.00 $1248.00 | 1 | |
(RS)-CPPG is a selective mGluR-8 modulator characterized by its unique chiral configuration, which enhances its affinity for the receptor's binding site. The compound's distinct molecular architecture promotes specific hydrogen bonding and hydrophobic interactions, optimizing receptor engagement. Its dynamic binding kinetics allow for precise modulation of receptor activity, potentially influencing intracellular signaling pathways and neuronal communication. The compound's stereochemistry may also play a role in its interaction with other molecular targets, further diversifying its functional profile. | ||||||
(RS)-MCPG | 146669-29-6 | sc-202325 | 5 mg | $137.00 | ||
A competitive antagonist at mGluR-8 and other group II metabotropic glutamate receptors, which may reduce mGluR-8 mediated signaling. | ||||||
UBP1112 | 339526-74-8 | sc-204368 sc-204368A | 10 mg 50 mg | $686.00 $1509.00 | 2 | |
UBP1112 is a selective modulator of mGluR-8, distinguished by its unique structural features that facilitate specific electrostatic interactions with the receptor. This compound exhibits a remarkable ability to stabilize the receptor in an active conformation, enhancing its signaling efficacy. The intricate balance of hydrophilic and lipophilic regions within UBP1112 contributes to its favorable binding kinetics, allowing for nuanced regulation of downstream signaling cascades. Its conformational flexibility may also enable interactions with various protein partners, broadening its functional implications. | ||||||
MTPG | 169209-66-9 | sc-204106 sc-204106A | 5 mg 50 mg | $119.00 $709.00 | ||
MTPG is a selective mGluR-8 modulator characterized by its unique binding affinity and conformational adaptability. This compound engages in specific hydrogen bonding and hydrophobic interactions with the receptor, promoting a distinct allosteric modulation. MTPG's kinetic profile reveals a rapid association and dissociation rate, allowing for precise temporal control of receptor activity. Its structural diversity enhances the potential for unique interactions with cellular pathways, influencing downstream effects. | ||||||
(RS)-MSPG | 169209-64-7 | sc-203247 sc-203247A | 5 mg 10 mg | $48.00 $201.00 | ||
(RS)-MSPG is a selective modulator of mGluR-8, distinguished by its ability to stabilize receptor conformations through unique electrostatic interactions. This compound exhibits a notable capacity for allosteric enhancement, facilitating nuanced signaling pathways. Its dynamic binding kinetics enable swift receptor activation, while its structural features promote specific interactions with lipid membranes, potentially influencing receptor localization and function within neuronal networks. | ||||||
L-γ-Carboxyglutamic acid | 53861-57-7 | sc-295277 sc-295277A | 10 mg 50 mg | $402.00 $1047.00 | ||
L-γ-Carboxyglutamic acid serves as a selective modulator of mGluR-8, characterized by its ability to engage in specific hydrogen bonding and ionic interactions that influence receptor dynamics. This compound demonstrates a unique capacity for conformational flexibility, allowing it to adapt to various binding sites. Its interactions with surrounding molecular environments can alter receptor affinity and efficacy, potentially impacting downstream signaling cascades in neural pathways. | ||||||
(S)-MCPG | 150145-89-4 | sc-202329 sc-202329A | 5 mg 25 mg | $146.00 $964.00 | ||
An enantiomer of MCPG, which acts as a competitive antagonist of mGluR-8 and can inhibit its signaling. | ||||||
2-Phenylglycine | 2835-06-5 | sc-238199 | 100 g | $38.00 | ||
An mGluR antagonist that can interact with mGluR-8 and attenuate its signal transduction. | ||||||
MPPG | 169209-65-8 | sc-203143 sc-203143A | 10 mg 50 mg | $175.00 $739.00 | ||
A selective antagonist for group II metabotropic glutamate receptors that can decrease activity at the mGluR-8 site. | ||||||
MAP4 | 157381-42-5 | sc-202221 | 5 mg | $40.00 | ||
A negative allosteric modulator of mGluR-8, directly inhibiting its function. | ||||||