(RS)-CPPG CAS: 183364-82-1
MF: C11H14NO5P
MW: 271.21
The most potent group II/III mGluR antagonist.

(RS)-CPPG (CAS 183364-82-1)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 100ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Alternate Names: (RS)-Alpha-cyclopropyl-4-phosphonophenylglycine
Application: (RS)-CPPG is the most potent group II/III mGluR antagonist
CAS Number: 183364-82-1
Purity: ≥98%
Molecular Weight: 271.21
Molecular Formula: C11H14NO5P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

(RS)-CPPG is the most potent group II/III mGluR antagonist, with approx. 20-fold selectivity for group III over group II. (RS)-CPPG is an inhibitor of mGluR-2, mGluR-3, mGluR-4, mGluR-6, mGluR-7 and mGLuR-8.


References

1. Toms, N.J., et al. 1996. Br. J. Pharmacol. 119: 851-854. PMID: 8922731
2. Jane, D.E., et al. 1996. Neuropharmacology 35: 1029-1035. PMID: 9121605
3. Schoepp, D.D., et al. 1999. Neuropharmacology. 38: 1431-1476. PMID: 10530808

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (>5 mg/ml), dilute aqueous base, and NaOH (100 mM, 27mg/100mM NaOH = 100mM stock at pH7).
Storage :
Store at 4° C
Melting Point :
304.03° C (Predicted)
Boiling Point :
541.54° C at 760 mmHg (Predicted)
Density :
1.57 g/cm3 (Predicted)
Refractive Index :
n20D 1.65 (Predicted)
IC50 :
mGlu group III : IC50 = 2.2 nM; mGlu group II: IC50 = 46.2 nM
pK Values :
pKa: 1.55 (Predicted), pKb: 10.39 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
2878
MDL Number :
MFCD00673967
SMILES :
C1CC1C(C2=CC=C(C=C2)P(=O)(O)O)(C(=O)O)N

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

(RS)-CPPG (CAS 183364-82-1)  Product Citations

See how others have used (RS)-CPPG (CAS 183364-82-1). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 32310084  Elife. 9:

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 98ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.