(RS)-CPPG (CAS 183364-82-1)
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(RS)-CPPG is the most potent group II/III mGluR antagonist, with approx. 20-fold selectivity for group III over group II. (RS)-CPPG is an inhibitor of mGluR-2, mGluR-3, mGluR-4, mGluR-6, mGluR-7 and mGLuR-8. (RS)-CPPG holds significance as an amino acid derivative under extensive scientific scrutiny due to its diverse biological effects. While the precise workings of (RS)-CPPG remain partially elusive, it is postulated that its influence might arise from interactions with proteins residing in cell membranes. Such interactions could potentially trigger or hinder a variety of cellular processes. Additionally, this compound could engage with diverse enzymes and receptors, thereby potentially inducing alterations in cellular signaling pathways and gene expression.
(RS)-CPPG (CAS 183364-82-1) References
- Novel metabotropic glutamate receptor negatively coupled to adenylyl cyclase in cultured rat cerebellar astrocytes. | Kanumilli, S., et al. 2004. Glia. 46: 1-7. PMID: 14999808
- The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist. | Toms, NJ., et al. 1996. Br J Pharmacol. 119: 851-4. PMID: 8922731
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(RS)-CPPG, 5 mg | sc-203448 | 5 mg | $416.00 | |||
(RS)-CPPG, 25 mg | sc-203448A | 25 mg | $1248.00 |