MEIOB inhibitors are a distinctive class of chemical compounds designed to target the MEIOB protein, which is implicated in various cellular processes, particularly those related to meiosis and gametogenesis. MEIOB (Meiosis Inhibitor of B) plays a crucial role in the regulation of meiosis, influencing the progression of this specialized type of cell division that is essential for the formation of gametes in sexually reproducing organisms. The inhibitors work by binding to the MEIOB protein, thereby disrupting its function and preventing it from interacting with other key proteins involved in the meiotic process. This targeted inhibition allows researchers to investigate the specific roles of MEIOB in meiosis and its broader implications in cellular biology.
In research applications, MEIOB inhibitors are utilized to explore the detailed mechanisms by which MEIOB influences meiosis and gamete formation. By inhibiting this protein, scientists can assess the resulting effects on meiotic progression, chromosomal dynamics, and overall cell division processes. This research is pivotal for understanding the underlying mechanisms that govern reproductive biology and the various factors that contribute to successful meiosis. Additionally, the study of MEIOB inhibitors aids in elucidating the complex interactions between meiosis and other cellular pathways, shedding light on the regulatory networks that maintain genomic integrity during cell division. As research on MEIOB inhibitors continues to unfold, these compounds are expected to play a critical role in advancing knowledge in the fields of cell biology, genetics, and reproductive science.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $82.00 $300.00 $1082.00 | 30 | |
DNA polymerase inhibitor that can impede DNA replication, thereby potentially affecting MEIOB's role in meiotic recombination. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Topoisomerase I inhibitor that can alter DNA topology and thereby potentially influencing MEIOB's interaction with DNA. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Topoisomerase II inhibitor that can affect DNA decatenation, potentially influencing MEIOB's role in meiotic recombination. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor that can change chromatin structure and thereby potentially influence the access of MEIOB to DNA. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor that can lead to demethylation of DNA and potentially affect the expression of MEIOB. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
Nucleotide synthesis inhibitor that can disrupt DNA synthesis and potentially affect processes MEIOB is involved in. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Microtubule stabilizer that can affect cell division, potentially disrupting processes that MEIOB is involved in during meiosis. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
DNA crosslinker that can impede DNA replication and transcription, potentially affecting MEIOB's function in meiotic recombination. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Transcription inhibitor that can prevent the transcription of many genes, potentially including MEIOB. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor that can lead to an increase in protein levels, potentially affecting protein turnover and influencing the levels of MEIOB in the cell. |