MAGE-B1 Activators
MAGE-B1 activators are a class of compounds that enhance the functional activity of MAGE-B1, a protein implicated in several cellular processes. These activators exert their effects by modulating distinct biochemical pathways that regulate the function of MAGE-B1. They include compounds such as Resveratrol and Curcumin, which influence the SIRT1 and NF-κB pathways respectively, leading to enhanced MAGE-B1 functional activity. Other compounds such as Sulforaphane and EGCG modulate the NRF2 and PI3K/AKT pathways respectively, leading to increased MAGE-B1 activity.
Capsaicin and Genistein, for example, work through the TRPV1 and ERK pathways respectively, promoting MAGE-B1 function. Berberine and Salicylic Acid are also part of this class, impacting AMPK and COX pathways respectively to upregulate MAGE-B1. Another compound, Indole-3-Carbinol, influences the AhR pathway, leading to enhanced MAGE-B1 functionality. Kaempferol and Lycopene affect the mTOR and PPAR pathways respectively, leading to enhanced MAGE-B1 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates the SIRT1 pathway. The activation of SIRT1 can lead to deacetylation of transcription factors that positively regulate MAGE-B1, enhancing its functional activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin inhibits the NF-κB pathway. Inhibition of NF-κB can increase MAGE-B1 activity by preventing its suppression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane activates the NRF2 pathway. NRF2 activation leads to upregulation of MAGE-B1, enhancing its function. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG inhibits the PI3K/AKT pathway, leading to increased MAGE-B1 activity, as PI3K/AKT negatively regulates MAGE-B1 function. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin activates the JNK pathway. JNK activation leads to enhanced MAGE-B1 functional activity, as JNK positively regulates MAGE-B1. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin activates the TRPV1 pathway. TRPV1 activation enhances MAGE-B1 functionality, as TRPV1 positively regulates MAGE-B1. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein inhibits the ERK pathway. ERK inhibition enhances MAGE-B1 activity, as ERK negatively regulates MAGE-B1. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine activates the AMPK pathway. AMPK activation enhances MAGE-B1 functionality, as AMPK positively regulates MAGE-B1. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $47.00 $94.00 $119.00 | 3 | |
Salicylic acid inhibits the COX pathway. COX inhibition enhances MAGE-B1 activity, as COX negatively regulates MAGE-B1. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
Indole-3-Carbinol activates the AhR pathway. AhR activation leads to enhanced MAGE-B1 functionality, as AhR positively regulates MAGE-B1. | ||||||