MAGE-B1 Activators

MAGE-B1 activators are a class of compounds that enhance the functional activity of MAGE-B1, a protein implicated in several cellular processes. These activators exert their effects by modulating distinct biochemical pathways that regulate the function of MAGE-B1. They include compounds such as Resveratrol and Curcumin, which influence the SIRT1 and NF-κB pathways respectively, leading to enhanced MAGE-B1 functional activity. Other compounds such as Sulforaphane and EGCG modulate the NRF2 and PI3K/AKT pathways respectively, leading to increased MAGE-B1 activity.

Capsaicin and Genistein, for example, work through the TRPV1 and ERK pathways respectively, promoting MAGE-B1 function. Berberine and Salicylic Acid are also part of this class, impacting AMPK and COX pathways respectively to upregulate MAGE-B1. Another compound, Indole-3-Carbinol, influences the AhR pathway, leading to enhanced MAGE-B1 functionality. Kaempferol and Lycopene affect the mTOR and PPAR pathways respectively, leading to enhanced MAGE-B1 activity.