MAGE-B1 Antibody (B-4): sc-271008
- MAGE-B1 Antibody (B-4) is a mouse monoclonal IgG1 κ MAGE-B1 antibody provided at 200 µg/ml
- raised against a peptide mapping within an internal region of MAGE-B1 of human origin
- MAGE-B1 Antibody (B-4) is recommended for detection of MAGE-B1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-MAGE-B1 Antibody (B-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MAGE-B1 Antibody (B-4) for WB applications. These reagents are now offered in bundles with MAGE-B1 Antibody (B-4) (see ordering information below).
MAGE-B1 Antibody (B-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects MAGE-B1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-MAGE-B1 antibody (B-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MAGE-B1 belongs to the melanoma-associated antigen (MAGE) family, which is known for eliciting immune responses against tumors. MAGE-B1 is primarily expressed in malignant tissues, making MAGE-B1 a valuable target for cancer immunotherapy, as expression remains largely absent in normal adult tissues, except in testis and placenta. MAGE-B1 plays a crucial role in tumor rejection by interacting with cytotoxic T lymphocytes, facilitating immune system recognition and elimination of cancer cells. Understanding MAGE-B1 function in tumor immunity is essential for developing effective immunotherapeutic strategies to enhance natural defenses against cancer.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MAGE-B1 Antibody (B-4) References:
- Mage-b4, a novel melanoma antigen (MAGE) gene specifically expressed during germ cell differentiation. | Osterlund, C., et al. 2000. Cancer Res. 60: 1054-61. PMID: 10706124
- A MAGE-A1 peptide is recognized on HLA-B7 human tumors by cytolytic T lymphocytes. | Luiten, R. and van der Bruggen, P. 2000. Tissue Antigens. 55: 149-52. PMID: 10746786
- Expression of MAGE, GAGE and BAGE genes in human liver diseases: utility as molecular markers for hepatocellular carcinoma. | Kobayashi, Y., et al. 2000. J Hepatol. 32: 612-7. PMID: 10782910
- Immunoreactivity with the anti-MAGE antibody 57B in malignant melanoma: frequency of expression and correlation with prognostic parameters. | Busam, KJ., et al. 2000. Mod Pathol. 13: 459-65. PMID: 10786815
- Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines. | Klein, C., et al. 2000. J Exp Med. 191: 1699-708. PMID: 10811863
- Melanoma antigen genes 1 and 2 are differentially expressed in human gastric and cardial carcinomas. | Granelli, P., et al. 2000. Scand J Gastroenterol. 35: 528-33. PMID: 10868457
- Genetic detection for micrometastasis in lymph node of biliary tract carcinoma. | Okami, J., et al. 2000. Clin Cancer Res. 6: 2326-32. PMID: 10873083
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAGE-B1 Antibody (B-4) | sc-271008 | 200 µg/ml | $316.00 | |||
MAGE-B1 Antibody (B-4): m-IgG Fc BP-HRP Bundle | sc-529097 | 200 µg Ab; 10 µg BP | $354.00 | |||
MAGE-B1 Antibody (B-4): m-IgGκ BP-HRP Bundle | sc-521815 | 200 µg Ab, 40 µg BP | $354.00 | |||
MAGE-B1 Antibody (B-4): m-IgG1 BP-HRP Bundle | sc-543316 | 200 µg Ab; 20 µg BP | $354.00 | |||
MAGE-B1 Antibody (B-4) AC | sc-271008 AC | 500 µg/ml, 25% agarose | $416.00 | |||
MAGE-B1 Antibody (B-4) HRP | sc-271008 HRP | 200 µg/ml | $316.00 | |||
MAGE-B1 Antibody (B-4) FITC | sc-271008 FITC | 200 µg/ml | $330.00 | |||
MAGE-B1 Antibody (B-4) PE | sc-271008 PE | 200 µg/ml | $343.00 | |||
MAGE-B1 Antibody (B-4) Alexa Fluor® 488 | sc-271008 AF488 | 200 µg/ml | $357.00 | |||
MAGE-B1 Antibody (B-4) Alexa Fluor® 546 | sc-271008 AF546 | 200 µg/ml | $357.00 | |||
MAGE-B1 Antibody (B-4) Alexa Fluor® 594 | sc-271008 AF594 | 200 µg/ml | $357.00 | |||
MAGE-B1 Antibody (B-4) Alexa Fluor® 647 | sc-271008 AF647 | 200 µg/ml | $357.00 | |||
MAGE-B1 Antibody (B-4) Alexa Fluor® 680 | sc-271008 AF680 | 200 µg/ml | $357.00 | |||
MAGE-B1 Antibody (B-4) Alexa Fluor® 790 | sc-271008 AF790 | 200 µg/ml | $357.00 | |||
MAGE-B1 (B-4) Neutralizing Peptide | sc-271008 P | 100 µg/0.5 ml | $68.00 |