Date published: 2025-9-9

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LYSMD3 Inhibitors

LYSMD3 inhibitors represent a class of chemical compounds designed to target a specific protein called LYSMD3 (Lysine-rich Small Membrane protein Domain-containing 3). LYSMD3 is a relatively newly discovered protein that plays a significant role in various cellular processes, particularly in the regulation of protein degradation and turnover. These inhibitors are designed to interfere with the activity of LYSMD3, modulating its function in a selective manner.LYSMD3 protein belongs to a family of proteins known as LYSMD proteins, which are characterized by the presence of a lysine-rich small membrane protein domain. LYSMD3, in particular, is believed to be involved in the recognition and degradation of specific target proteins within the cell.

LYSMD3 inhibitors are designed to bind to LYSMD3, either competitively or allosterically, inhibiting its ability to interact with its substrates or interfering with its enzymatic activity. By doing so, these inhibitors can influence protein stability and degradation pathways, potentially leading to downstream effects on cellular processes. LYSMD3 inhibitors is still relatively nascent, and their precise mechanisms of action and potential applications are subjects of ongoing investigation. However, their development represents an exciting avenue in the field of molecular biology and drug discovery, as they offer the potential to manipulate cellular protein degradation pathways in a controlled manner.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$52.00
$87.00
7
(1)

Interferes with aldehyde dehydrogenase, which may affect histone modification and thus LYSMD3.

Tranylcypromine

13492-01-8sc-200572
sc-200572A
1 g
5 g
$172.00
$587.00
5
(1)

A non-selective monoamine oxidase inhibitor that can alter histone demethylation processes.

Parthenolide

20554-84-1sc-3523
sc-3523A
50 mg
250 mg
$79.00
$300.00
32
(2)

Targets NF-κB, a transcription factor that can regulate genes including those affecting LYSMD3.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

Inhibits MEK, which may alter signaling pathways that indirectly influence LYSMD3 activity.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$65.00
$267.00
257
(3)

Inhibits JNK, potentially affecting transcription factors regulating LYSMD3.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

P38 MAP kinase inhibitor, could impact cellular processes related to LYSMD3 function.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

PI3K inhibitor that may affect downstream signaling pathways involving LYSMD3.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

Inhibits MEK1/2 and may alter signaling pathways that indirectly influence LYSMD3 activity.

Chetomin

1403-36-7sc-202535
sc-202535A
1 mg
5 mg
$182.00
$661.00
10
(1)

Hinders hypoxia-inducible factor (HIF) activity, possibly affecting LYSMD3-regulated genes.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

Proteasome inhibitor, could affect the degradation of regulatory proteins related to LYSMD3.