LOC728478 Inhibitors
Wortmannin and Kenpaullone, inhibit key enzymes like PI3K and cyclin-dependent kinases, which are pivotal in signaling pathways that govern cell proliferation, survival, and metabolism. These pathways could intersect with the function of LOC728478, and modulation thereof may alter the protein's activity. Trichostatin A and SB431542 target epigenetic regulators and growth factor signaling, respectively, suggesting that if LOC728478 is implicated in gene expression or growth factor response, these compounds could indirectly influence its activity.
Further, compounds like SP600125 and Y-27632 would be of interest if LOC728478 is associated with stress response or cytoskeletal arrangement due to their action on JNK signaling and Rho-associated kinases. In scenarios where inflammation or differentiation is relevant, NS-398 and PD173074 could play a role by affecting prostaglandin synthesis and fibroblast growth factor signaling pathways. Finally, LY83583, KN-93, Gö 6983, and Ivermectin represent inhibitors of diverse cellular processes such as cyclic nucleotide signaling, calcium/calmodulin-dependent processes, protein kinase C activity, and ion channel conductivity. If LOC728478 is a part of or regulated by these processes, the activity of the protein could be indirectly modulated by these compounds.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor that can alter PI3K/AKT signaling, possibly affecting LOC728478 if it is part of this pathway. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that can modify chromatin structure and gene expression, possibly influencing LOC728478 if it is regulated by acetylation. | ||||||
Kenpaullone | 142273-20-9 | sc-200643 sc-200643A sc-200643B sc-200643C | 1 mg 5 mg 10 mg 25 mg | $60.00 $150.00 $226.00 $495.00 | 1 | |
A cyclin-dependent kinase inhibitor that can interfere with cell cycle progression, possibly affecting LOC728478 if it is involved in cell division. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
An inhibitor of the TGF-beta receptor that can block TGF-beta signaling, possibly affecting LOC728478 if it is part of this pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK signaling that can alter stress response pathways, possibly modulating LOC728478 activity if it is stress-responsive. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor that can affect cytoskeleton dynamics, possibly affecting LOC728478 if it is involved in cell morphology or motility. | ||||||
NS-398 | 123653-11-2 | sc-200604 sc-200604A | 5 mg 25 mg | $84.00 $332.00 | 9 | |
A COX-2 inhibitor that can reduce prostaglandin synthesis, possibly affecting LOC728478 if it is involved in inflammation. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $46.00 $140.00 $680.00 | 16 | |
An FGFR inhibitor that can block fibroblast growth factor signaling, possibly modulating LOC728478 activity if it is part of this pathway. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
A CaMKII inhibitor that can influence calcium/calmodulin signaling, possibly affecting LOC728478 if it is calcium-responsive. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
A PKC inhibitor that can alter protein kinase C signaling, possibly influencing LOC728478 activity if it is part of this pathway. | ||||||