The chemical class of LOC100040307 Inhibitors represents a specific group of compounds designed to selectively target and inhibit the activity of the gene product of LOC100040307. This gene, identified through advanced genetic sequencing and analysis, plays a significant role in various cellular functions and processes. The function of LOC100040307 is particularly context-dependent, meaning its role can vary significantly depending on the cellular environment and external stimuli. The inhibitors tailored to this gene are specialized in their mechanism of action, focusing on binding to the proteins or enzymes produced as a result of LOC100040307 expression. This binding is a critical aspect of these inhibitors as it directly influences the biological pathways in which the LOC100040307 gene product is involved. By modulating the activity of this gene product, these inhibitors affect the associated cellular processes.
The development of LOC100040307 Inhibitors is a complex and interdisciplinary process, involving molecular biology, chemistry, and a deep understanding of gene function and expression. This process starts with an extensive study of the structure and function of the target gene product. Techniques like X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational molecular modeling are often employed to gain detailed insights into the target molecule. This knowledge is crucial for the rational design of inhibitors that are both effective and highly selective. Typically, these inhibitors are small molecules, designed to efficiently penetrate cell membranes and engage in a stable and potent interaction with their target. The molecular design of these inhibitors is carefully optimized to ensure robust interaction with the target molecule, typically involving the formation of hydrogen bonds, hydrophobic interactions, and van der Waals forces. The effectiveness of these inhibitors is evaluated through various in vitro biochemical assays. These assays play a vital role in assessing the inhibitors' potency and specificity, measuring their ability to inhibit the gene product's activity. These studies provide essential data on the inhibitors' behavior, laying the groundwork for further research into their interaction dynamics and mechanism of action.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Binds to RNA polymerase and inhibits RNA synthesis, which may reduce gene expression levels. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $163.00 $316.00 | 436 | |
Causes premature chain termination during translation, potentially reducing protein levels. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Inhibits histone deacetylases, affecting chromatin structure and potentially downregulating gene expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inhibits topoisomerase I, preventing DNA unwinding and potentially affecting transcription. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Inhibits transcriptional activity by affecting RNA polymerase II, potentially reducing gene expression. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
Inhibits transcription elongation by targeting RNA polymerase II, possibly decreasing gene expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Specifically inhibits RNA polymerase II in eukaryotes, which can reduce mRNA production. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Intercalates into DNA and inhibits RNA polymerase movement, affecting gene transcription. | ||||||
Siomycin A | 12656-09-6 | sc-202339 sc-202339-CW sc-202339A sc-202339B | 500 µg 500 µg 2.5 mg 25 mg | $439.00 $449.00 $1326.00 $10200.00 | 4 | |
A thiopeptide compound that inhibits transcription by targeting RNA polymerase, reducing gene expression. | ||||||
Lactacystin | 133343-34-7 | sc-3575 sc-3575A | 200 µg 1 mg | $165.00 $575.00 | 60 | |
Inhibits proteasome function, which may indirectly affect levels of proteins that regulate gene expression. |