Date published: 2025-10-10

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LOC100040307 Inhibitors

The chemical class of LOC100040307 Inhibitors represents a specific group of compounds designed to selectively target and inhibit the activity of the gene product of LOC100040307. This gene, identified through advanced genetic sequencing and analysis, plays a significant role in various cellular functions and processes. The function of LOC100040307 is particularly context-dependent, meaning its role can vary significantly depending on the cellular environment and external stimuli. The inhibitors tailored to this gene are specialized in their mechanism of action, focusing on binding to the proteins or enzymes produced as a result of LOC100040307 expression. This binding is a critical aspect of these inhibitors as it directly influences the biological pathways in which the LOC100040307 gene product is involved. By modulating the activity of this gene product, these inhibitors affect the associated cellular processes.

The development of LOC100040307 Inhibitors is a complex and interdisciplinary process, involving molecular biology, chemistry, and a deep understanding of gene function and expression. This process starts with an extensive study of the structure and function of the target gene product. Techniques like X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational molecular modeling are often employed to gain detailed insights into the target molecule. This knowledge is crucial for the rational design of inhibitors that are both effective and highly selective. Typically, these inhibitors are small molecules, designed to efficiently penetrate cell membranes and engage in a stable and potent interaction with their target. The molecular design of these inhibitors is carefully optimized to ensure robust interaction with the target molecule, typically involving the formation of hydrogen bonds, hydrophobic interactions, and van der Waals forces. The effectiveness of these inhibitors is evaluated through various in vitro biochemical assays. These assays play a vital role in assessing the inhibitors' potency and specificity, measuring their ability to inhibit the gene product's activity. These studies provide essential data on the inhibitors' behavior, laying the groundwork for further research into their interaction dynamics and mechanism of action.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$95.00
$322.00
$663.00
$1438.00
6
(1)

Binds to RNA polymerase and inhibits RNA synthesis, which may reduce gene expression levels.

Puromycin

53-79-2sc-205821
sc-205821A
10 mg
25 mg
$163.00
$316.00
436
(1)

Causes premature chain termination during translation, potentially reducing protein levels.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Inhibits histone deacetylases, affecting chromatin structure and potentially downregulating gene expression.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Inhibits topoisomerase I, preventing DNA unwinding and potentially affecting transcription.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Inhibits transcriptional activity by affecting RNA polymerase II, potentially reducing gene expression.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

Inhibits transcription elongation by targeting RNA polymerase II, possibly decreasing gene expression.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

Specifically inhibits RNA polymerase II in eukaryotes, which can reduce mRNA production.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Intercalates into DNA and inhibits RNA polymerase movement, affecting gene transcription.

Siomycin A

12656-09-6sc-202339
sc-202339-CW
sc-202339A
sc-202339B
500 µg
500 µg
2.5 mg
25 mg
$439.00
$449.00
$1326.00
$10200.00
4
(1)

A thiopeptide compound that inhibits transcription by targeting RNA polymerase, reducing gene expression.

Lactacystin

133343-34-7sc-3575
sc-3575A
200 µg
1 mg
$165.00
$575.00
60
(2)

Inhibits proteasome function, which may indirectly affect levels of proteins that regulate gene expression.