Date published: 2025-11-28

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LEMD1 Activators

The chemical class known as LEMD1 Activators refers to a specific group of compounds recognized for their ability to modulate the activity of the LEMD1 gene. LEMD1, or LEM Domain-Containing Protein 1, is a gene encoding a protein that contains a LEM (Lap2, emerin, and MAN1) domain, which is often involved in protein-protein interactions and nuclear envelope organization. While the exact function of LEMD1 is not fully elucidated, it is believed to participate in various cellular processes, including chromatin organization, nuclear envelope dynamics, and cellular signaling. Activators of LEMD1 are substances capable of enhancing the expression or function of this gene, potentially influencing downstream cellular pathways and biological responses associated with its activity.

Identifying compounds as LEMD1 Activators typically involves intricate screening processes aimed at evaluating their ability to interact with regulatory elements of the LEMD1 gene or modulate the activity of proteins associated with its expression or function. These activators may operate through diverse mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for LEMD1 gene expression, or modulating post-translational modifications of the LEMD1 protein. Understanding the molecular mechanisms underlying LEMD1 activation by these compounds is crucial for unraveling the biological functions of LEMD1 and its potential roles in cellular physiology. Further research into LEMD1 Activators may provide insights into novel cellular pathways and contribute to a deeper understanding of LEMD1's function in nuclear organization and cellular dynamics.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

A metabolite of vitamin A that can regulate gene transcription by activating nuclear receptors, potentially affecting LEMD1 expression.

Adenosine 3′,5′-cyclic monophosphate

60-92-4sc-217584
sc-217584A
sc-217584B
sc-217584C
sc-217584D
sc-217584E
100 mg
250 mg
5 g
10 g
25 g
50 g
$114.00
$175.00
$260.00
$362.00
$617.00
$1127.00
(1)

A cAMP analog that may stimulate gene expression by activating protein kinase A and subsequent transcription factors.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Affects glycogen synthase kinase-3 (GSK-3) activity, possibly altering transcription factor activity and gene expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

An activator of adenylate cyclase, which can increase cAMP levels and may influence gene transcription through CREB activation.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

A diacylglycerol analog that activates protein kinase C (PKC) and might modulate gene expression through various signaling pathways.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

An inhibitor of histone deacetylases that can change chromatin structure and potentially influence gene expression.

Atrazine

1912-24-9sc-210846
5 g
$165.00
1
(1)

An herbicide that can disrupt endocrine function and might indirectly affect gene expression through hormonal pathways.

Bisphenol A

80-05-7sc-391751
sc-391751A
100 mg
10 g
$300.00
$490.00
5
(0)

Known to interact with estrogen receptors and may influence gene expression through hormone-responsive elements.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A DNA methyltransferase inhibitor that may cause hypomethylation of DNA and affect gene expression.

Butylated hydroxyanisole

25013-16-5sc-252527
sc-252527A
5 g
100 g
$29.00
$96.00
1
(0)

An antioxidant that might influence gene expression by affecting oxidative stress response signaling pathways.