The chemical class known as LEMD1 Activators refers to a specific group of compounds recognized for their ability to modulate the activity of the LEMD1 gene. LEMD1, or LEM Domain-Containing Protein 1, is a gene encoding a protein that contains a LEM (Lap2, emerin, and MAN1) domain, which is often involved in protein-protein interactions and nuclear envelope organization. While the exact function of LEMD1 is not fully elucidated, it is believed to participate in various cellular processes, including chromatin organization, nuclear envelope dynamics, and cellular signaling. Activators of LEMD1 are substances capable of enhancing the expression or function of this gene, potentially influencing downstream cellular pathways and biological responses associated with its activity.
Identifying compounds as LEMD1 Activators typically involves intricate screening processes aimed at evaluating their ability to interact with regulatory elements of the LEMD1 gene or modulate the activity of proteins associated with its expression or function. These activators may operate through diverse mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for LEMD1 gene expression, or modulating post-translational modifications of the LEMD1 protein. Understanding the molecular mechanisms underlying LEMD1 activation by these compounds is crucial for unraveling the biological functions of LEMD1 and its potential roles in cellular physiology. Further research into LEMD1 Activators may provide insights into novel cellular pathways and contribute to a deeper understanding of LEMD1's function in nuclear organization and cellular dynamics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A metabolite of vitamin A that can regulate gene transcription by activating nuclear receptors, potentially affecting LEMD1 expression. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
A cAMP analog that may stimulate gene expression by activating protein kinase A and subsequent transcription factors. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Affects glycogen synthase kinase-3 (GSK-3) activity, possibly altering transcription factor activity and gene expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
An activator of adenylate cyclase, which can increase cAMP levels and may influence gene transcription through CREB activation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
A diacylglycerol analog that activates protein kinase C (PKC) and might modulate gene expression through various signaling pathways. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An inhibitor of histone deacetylases that can change chromatin structure and potentially influence gene expression. | ||||||
Atrazine | 1912-24-9 | sc-210846 | 5 g | $165.00 | 1 | |
An herbicide that can disrupt endocrine function and might indirectly affect gene expression through hormonal pathways. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Known to interact with estrogen receptors and may influence gene expression through hormone-responsive elements. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that may cause hypomethylation of DNA and affect gene expression. | ||||||
Butylated hydroxyanisole | 25013-16-5 | sc-252527 sc-252527A | 5 g 100 g | $29.00 $96.00 | 1 | |
An antioxidant that might influence gene expression by affecting oxidative stress response signaling pathways. | ||||||