KRTAP1-3 Inhibitors
KRTAP1-3 inhibitors like Cycloheximide inhibits general protein synthesis, which can lead to a reduction in KRTAP1-3 levels. MG132 interferes with the ubiquitin-proteasome degradation pathway, potentially altering the turnover of proteins that regulate KRTAP1-3. Retinoic acid and tretinoin, both involved in gene expression modulation through retinoid-responsive elements, can influence the transcriptional level of KRTAP1-3. Minoxidil, finasteride, and spironolactone act on hair follicle biology by affecting blood flow and hormonal balance, which, in turn, can alter the expression of KRTAP1-3. Copper sulfate's role as a cofactor for various enzymes can have downstream effects on hair follicle function and KRTAP1-3.
Zinc pyrithione, with its antifungal properties, changes the scalp environment, which can impact KRTAP1-3 stability or expression in hair. Bimatoprost, a prostaglandin analog, affects the hair growth cycle and can thus influence KRTAP1-3 expression. Ketoconazole's antifungal and anti-androgenic effects can modify the hair follicle milieu, potentially affecting KRTAP1-3. Caffeine is known to stimulate hair follicle activity, which may lead to changes in KRTAP1-3 expression.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Inhibits protein biosynthesis, indirectly reducing KRTAP1-3 levels by preventing its synthesis. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor that can increase the levels of proteins that negatively regulate KRTAP1-3 stability or function. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Modulates gene expression, which can alter KRTAP1-3 expression through retinoid-responsive elements. | ||||||
Minoxidil (U-10858) | 38304-91-5 | sc-200984 sc-200984A | 100 mg 1 g | $69.00 $351.00 | ||
Vasodilator that can affect hair follicle biology and indirectly the expression or function of KRTAP1-3. | ||||||
Finasteride | 98319-26-7 | sc-203954 | 50 mg | $105.00 | 3 | |
Inhibits 5-alpha reductase, altering hormone levels and potentially affecting KRTAP1-3 expression in hair follicles. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $109.00 | 3 | |
Antagonizes androgen receptors and can indirectly influence KRTAP1-3 expression by modulating pathways. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Can act as a cofactor for enzymes that regulate hair follicle function, potentially influencing KRTAP1-3. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Antifungal agent that can alter scalp conditions and indirectly affect KRTAP1-3 expression or stability in hair follicles. | ||||||
Bimatoprost | 155206-00-1 | sc-205224 sc-205224A | 1 mg 5 mg | $120.00 $464.00 | 1 | |
Prostaglandin analog that can affect hair growth cycle, possibly influencing KRTAP1-3 expression. | ||||||
Ketoconazole | 65277-42-1 | sc-200496 sc-200496A | 50 mg 500 mg | $63.00 $265.00 | 21 | |
Antifungal and anti-androgenic properties may affect hair follicle environment and KRTAP1-3 expression. | ||||||