The chemical class named KLK4 Activators primarily consists of compounds that can indirectly influence the activity of KLK4. These activators function through various mechanisms, including hormonal regulation, modification of gene expression, and alteration of cellular signaling pathways.
KLK4 activators may exert their effects by modulating the expression of KLK4 at the transcriptional level or by influencing the local tissue environment, thereby indirectly affecting KLK4's proteolytic activity. For instance, compounds like 1,25-Dihydroxyvitamin D3 and androgens can enhance KLK4 expression in specific tissues, such as prostate cells, by interacting with their respective receptors. On the other hand, molecules like epigallocatechin gallate and curcumin can modify the broader cellular context, potentially impacting the regulation and activity of KLK4. These activators are important in research, particularly in understanding the complex regulatory mechanisms of KLK4 in various physiological and pathological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $325.00 $632.00 $1428.00 $2450.00 $400.00 | 32 | |
Stimulates KLK4 expression in prostate cancer cells by activating Vitamin D Receptor (VDR), potentially enhancing KLK4 activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A catechin in green tea, shown to modify the activity of various kallikreins, possibly influencing KLK4 indirectly. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Can modulate KLK4 expression, suggesting indirect influence on KLK4 activity through estrogen receptors. | ||||||
Finasteride | 98319-26-7 | sc-203954 | 50 mg | $103.00 | 3 | |
A 5α-reductase inhibitor, alters androgen metabolism, potentially influencing KLK4 expression in prostate tissue. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influences differentiation and proliferation in various tissues, possibly affecting KLK4 expression indirectly. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Found in plants, Quercetin can modulate various enzymes and receptors, potentially influencing KLK4 activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A compound from turmeric, known to affect numerous signaling pathways, potentially influencing KLK4 indirectly. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
An environmental estrogen, can modulate gene expression, potentially affecting KLK4 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A polyphenol with various biological activities, could indirectly influence KLK4 expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
A compound found in cruciferous vegetables, known to influence various signaling pathways, affecting KLK4. | ||||||