Date published: 2025-12-11

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KLK4 Activators

The chemical class named KLK4 Activators primarily consists of compounds that can indirectly influence the activity of KLK4. These activators function through various mechanisms, including hormonal regulation, modification of gene expression, and alteration of cellular signaling pathways.

KLK4 activators may exert their effects by modulating the expression of KLK4 at the transcriptional level or by influencing the local tissue environment, thereby indirectly affecting KLK4's proteolytic activity. For instance, compounds like 1,25-Dihydroxyvitamin D3 and androgens can enhance KLK4 expression in specific tissues, such as prostate cells, by interacting with their respective receptors. On the other hand, molecules like epigallocatechin gallate and curcumin can modify the broader cellular context, potentially impacting the regulation and activity of KLK4. These activators are important in research, particularly in understanding the complex regulatory mechanisms of KLK4 in various physiological and pathological processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$325.00
$632.00
$1428.00
$2450.00
$400.00
32
(2)

Stimulates KLK4 expression in prostate cancer cells by activating Vitamin D Receptor (VDR), potentially enhancing KLK4 activity.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

A catechin in green tea, shown to modify the activity of various kallikreins, possibly influencing KLK4 indirectly.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$62.00
$178.00
8
(1)

Can modulate KLK4 expression, suggesting indirect influence on KLK4 activity through estrogen receptors.

Finasteride

98319-26-7sc-203954
50 mg
$103.00
3
(1)

A 5α-reductase inhibitor, alters androgen metabolism, potentially influencing KLK4 expression in prostate tissue.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Influences differentiation and proliferation in various tissues, possibly affecting KLK4 expression indirectly.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Found in plants, Quercetin can modulate various enzymes and receptors, potentially influencing KLK4 activity.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

A compound from turmeric, known to affect numerous signaling pathways, potentially influencing KLK4 indirectly.

Bisphenol A

80-05-7sc-391751
sc-391751A
100 mg
10 g
$300.00
$490.00
5
(0)

An environmental estrogen, can modulate gene expression, potentially affecting KLK4 activity.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

A polyphenol with various biological activities, could indirectly influence KLK4 expression.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

A compound found in cruciferous vegetables, known to influence various signaling pathways, affecting KLK4.