Klk1b3 Inhibitors
Klk1b3 inhibitors belong to a class of chemical compounds designed to selectively target and interfere with the activity of Klk1b3, a protein encoded by the Klk1b3 gene. Klk1b3, also known as Kallikrein 1b3, is a member of the kallikrein-related peptidase family. These enzymes are involved in the proteolytic cleavage of proteins and peptides and have been implicated in various physiological processes.
The primary mechanism of action for Klk1b3 inhibitors typically involves their interaction with the Klk1b3 protein or its associated molecules, leading to the disruption of its normal proteolytic function. By inhibiting Klk1b3, these compounds have the potential to modulate cellular processes where this enzyme plays a role, although the specific functions and substrates of Klk1b3 are still the subject of ongoing research. Scientists studying Klk1b3 inhibitors aim to elucidate the precise roles and functions of Klk1b3 in cellular biology, contributing to our understanding of its significance within cellular processes and proteolytic pathways. These inhibitors serve as valuable tools for advancing our knowledge of Klk1b3 and its potential roles in physiological or pathological contexts. In this context, they contribute to expanding our understanding of the intricate world of proteolytic enzymes and their roles in cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
An inhibitor of DNA topoisomerase I, it interferes with DNA replication and transcription processes. | ||||||
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $142.00 $558.00 | 4 | |
Alkaloid that intercalates with DNA and inhibits several DNA-associated enzymes, potentially reducing gene transcription. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
A cyclin-dependent kinase inhibitor that can suppress cell cycle progression and consequently gene transcription. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
It binds tightly to DNA and is known to interfere with the synthesis of RNA, thus inhibiting gene expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
A flavonoid that has been shown to modulate protein kinase pathways involved in transcription regulation. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Known to affect multiple enzymes involved in the DNA checkpoint and repair, may influence gene expression indirectly. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can influence the Akt signaling pathway, potentially modulating protein transcription and expression. | ||||||
Siomycin A | 12656-09-6 | sc-202339 sc-202339-CW sc-202339A sc-202339B | 500 µg 500 µg 2.5 mg 25 mg | $439.00 $449.00 $1326.00 $10200.00 | 4 | |
A thiazole compound that inhibits FOXM1 transcription factor and could thereby reduce gene expression. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $32.00 $210.00 $720.00 $1128.00 $2302.00 $3066.00 $5106.00 | 22 | |
A natural product that has been found to modulate various signaling pathways and potentially alter gene expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A MEK inhibitor that can prevent the activation of MAP kinase pathway, potentially reducing the transcription of certain genes. | ||||||